Results 111 to 120 of about 529,537 (309)

Regional economic dynamics and convergence in the european union [PDF]

open access: yes
Deepening in the European Union (EU) integration process has enhanced the question of economic disparities at a regional level. The convergence process observed until the late seventies was exhausted onwards in coincidence with important changes in the ...
Antonio Jose Mora   +3 more
core   +1 more source

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

open access: yesAdvanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim   +12 more
wiley   +1 more source

Spatial Inequality, Migration and Economic Growth in Chile [PDF]

open access: yes
Between 1975 and 2000, annual per-capita GDP in Chile grew at 5%. Yet, regions did not benefit equally: poverty declined significantly in all regions but regional income inequality remained stagnant.
Arístides Torche, Raimundo Soto
core  

β‐Triketone‐Based Ionizable Cationic Lipids Synthesized via Click Chemistry for siRNA Delivery

open access: yesAdvanced Science, EarlyView.
This study innovatively applies β‐triketone‐based click chemistry in the synthesis of ionizable cationic lipids (ICLs), which allows the generation of a lipid library in large quantities and in a short time. The ICLs identified achieved effective lipid nanoparticles‐mediated hepatic gene silencing in vivo using siRNA, and computational simulations are ...
Huatian Li   +7 more
wiley   +1 more source

A THEORETICAL DEVELOPMENT AND EMPIRICAL TEST ON THE CONVERGENCE OF AGRICULTURAL PRODUCTIVITY IN THE USA [PDF]

open access: yes
This study explores the evidence of convergence in the U.S agriculture sector by using the state level total factor productivity (TFP) data. The empirical investigation conducted in this study does not find any evidence of convergence while looking at ...
Paudel, Krishna P.   +2 more
core   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Convergence in Per Capita Income and Migration Across the Swedish Counties 1906-1990 [PDF]

open access: yes
This paper finds strong and robust evidence of convergence in per capita income across the twenty-four Swedish counties 1906-1990. It is found that migration has a positive effect, albeit small, on the speed of convergence. Holding net migration constant,
Persson, Joakim
core   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

open access: yesAdvanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu   +13 more
wiley   +1 more source

Central Government Transfers and Regional Convergence in Portugal [PDF]

open access: yes
Over the last decades, the Portuguese economy exhibited an outstanding growth performance. This period of fast economic growth allowed the country to consistently reduce its income gap with respect to the EU average. In spite of this, regions in Portugal
Marta Ferreira Dias, Ricardo Silva
core  

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