Results 31 to 40 of about 2,293,025 (290)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Padjadjaran: Jurnal Ilmu Hukum, 2015 Abstrak Hubungan antara kewenangan pusat dengan daerah di Indonesia mengalami pasang surut sesuai rezim penyelenggaraan negara. Sejak reformasi, telah terdapat beberapa kali perubahan format otonomi daerah.
Yusdianto Yusdianto
doaj +1 more source
This chapter explores recent developments in regional cooperation and integration over migration governance. It provides an overview of how, and why, regional migration governance has become involved in the governance of human mobility, and of the relationship between regional and national/global migration governance respectively.
Lietaert, Ine, Pécoud, Antoine
openaire +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Physico-chemical characteristics of pomegranate accessions from the Kurdistan Region, Iraq [PDF]
Journal of Agricultural Sciences (Belgrade), 2018 Some physico-chemical properties of ten pomegranate accessions collected from different districts in the Kurdistan region of Iraq were investigated in this paper.
Mohammad Saadatian +5 more
doaj
ROLE OF REGIONAL HEAD OF STATE’S ATTITUDES IN IMPLEMENTATION OF FINANCE POLICY ABOUT THE GOVERNMENT ACCOUNTING STANDARDS IN INDONESIA [PDF]
, 2014 ndonesian state financial policies have undergone major changes since the release the Law on State Finance package in 2003 and 2004 as well as the Law on Local Government Package of 2004.
Kismartini, Kismartini +3 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effects of Allium siculum in ethylene glycol induced kidney stone in male albino rats
Kuwait Journal of Science, 2021 The current study attempts to find the curative effects of Allium siculum on ethylene glycol induced kidney stone in male albino rats. Twenty two male albino rats were divided into four experimental groups. Group A represented the control.
Sarbast Ahmad Mahmud +4 more
doaj +1 more source