Results 41 to 50 of about 3,332,908 (352)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Contemporary Regional Studies – Theory, Methodology and Practice

open access: yesStudia Regionalne i Lokalne, 2006
The paper offers a review of the evolution in defining and describing regions, showing mutual relationships between particular approaches and logical succession between various analytical concepts of the region.
Iwona Sagan
doaj  

The student review of the science curriculum [PDF]

open access: yes, 2005
This paper presents some of the main findings of a student-led review of the science curriculum in England. Over 350 students, aged 16-19, designed possible questions for a web-based questionnaire at regional meetings held across England.
Murray, Ian, Reiss, Michael
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Terminological Traps for Russian Bilingual Scientists

open access: yesPolylinguality and Transcultural Practices
This study addresses the issue of terminological pitfalls encountered by Russian bilingual scholars working in the field of linguoculturology and other humanities disciplines.
Chimiza K. Lamazhaa
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regional surname affinity: a spatial network approach [PDF]

open access: yes, 2019
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

İÇ GÖÇ ÇIKIŞINDA GSYİH BİLEŞENLERİNİN ETKİSİ VE BİLECİK ÖRNEĞİ

open access: yesEkonomi Maliye İşletme Dergisi, 2019
Ravenstein’dan beri ekonominin iç göç çıkışlarının belirleyicilerinden olduğu kabul edilmektedir. Ekonomide de tarım dışı üretim hacminin etkisi vurgulanmaktadır.
Murat ÇİFTÇİ
doaj  

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