Results 51 to 60 of about 834,286 (302)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
In a paper published in 2020, Philip McCann gives a qualitative overview of "the Nordic contribution to regional science", which, however, only includes contributions by Swedish regional science researchers.
Karlsson, Charlie +4 more
core +1 more source
İÇ GÖÇ ÇIKIŞINDA GSYİH BİLEŞENLERİNİN ETKİSİ VE BİLECİK ÖRNEĞİ
Ekonomi Maliye İşletme Dergisi, 2019 Ravenstein’dan beri ekonominin iç göç çıkışlarının belirleyicilerinden olduğu kabul edilmektedir. Ekonomide de tarım dışı üretim hacminin etkisi vurgulanmaktadır.
Murat ÇİFTÇİ
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
CAPTURING REGIONAL BENEFITS FROM SCIENCE AND TECHNOLOGY: THE QUESTION OF REGIONAL APPROPRIABILITY
Prometheus, 1991 The term ‘appropriability’ usually refers to the ability of a business entity to capture benefits from its investment in science and technology. In this paper it is suggested that governments should focus on regional appropriability, the ability of the ...
Fred Jevons, Marc Saupin
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Regional university as a center of science
Высшее образование в России, 2022 The author analyses the forms and mechanisms of the determination of the scientific research activity of a regional university functioning in the multicultural society (in the Kabardino-Balkar Republic as the example).
Petr A. Savintsev
doaj
REGIONAL ECONOMICS AS A PART OF REGIONAL SCIENCES
, 2021 Regional science is a multidisciplinary field which started to develop significantly in the 1950s. The development of regional sciences relies on the study of theories and tools that explain the mutual interactions of time and space (location) and their impact on society and its activities in a defined space.
openaire +2 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source