Results 61 to 70 of about 3,332,908 (352)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Problematyka metodologiczna studiów regionalnych

open access: yesStudia Regionalne i Lokalne, 2005
Praca ta stanowi wprowadzenie do problematyki metodologicznej studiów regionalnych. Składa się z trzech części. Pierwsza część omawia charakter studiów regionalnych, do których zalicza się Regional Science jako reprezentacyjną formę instytucjonalno ...
Zbyszko Chojnicki
doaj  

The Contributions of Regional Knowledge Networks Researching Environmental Changes in Latin America and Africa: a Synthesis of what they can do and why they can be policy relevant

open access: yesEcology and Society, 2013
We provide a synthesis of what regional scientific research networks in less developed regions of the world can do and why they might be relevant for societal decisions and practice.
Myanna Lahsen   +8 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Associations for Citizen Science: Regional Knowledge, Global Collaboration

open access: yesCitizen Science: Theory and Practice, 2016
Since 2012, three organizations advancing the work of citizen science practitioners have arisen in different regions: The primarily US-based but globally open Citizen Science Association (CSA), the European Citizen Science Association (ECSA), and the ...
Martin Storksdieck   +9 more
doaj   +1 more source

Bhashaposhini Suchika (1977 –1992) [ഭാഷാപോഷിണി സൂചിക 1971-1992] [PDF]

open access: yes, 2002
The journal Bhashaposhini is an authentic source for stdueis and research in areas of Malayalam literature, history and culture. It started publication in 1987 and after completion of 49 volumes ceased publication in 1942.
Laila, T. Abraham, Sisupalan, K.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Współczesne studia regionalne – teoria i metodologia, a także praktyka

open access: yesStudia Regionalne i Lokalne, 2004
Artykuł podejmuje próbę przekrojowego przedstawienia ewolucji sposobów definiowania i opisu regionów, wskazując na ich wzajemne wynikanie oraz logiczne następstwo kolejnych analitycznych koncepcji regionu.
Iwona Sagan
doaj  

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