Results 81 to 90 of about 3,173,534 (349)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Aggregate and Regional Economic Effects of New Railway Infrastructure [PDF]

Economists expect positive returns to investments in infrastructure. However a project with higher national returns might have less favorable effects on a regional level than the alternative.
Richard Sellner, Wolfang Polasek, Wolfang Schwarzbauer   +2 more
core   +4 more sources

Editorial: developments at the Annals of regional science 2020-2021. [PDF]

Ann Reg Sci, 2022
Andersson M, Kim BHS, Kohlhase JE.
europepmc   +1 more source

A flexible modeling framework to estimate interregional trade patterns and input-output accounts [PDF]

This study implements and tests a mathematical programming model to estimate interregional, interindustry transaction flows in a national system of economic regions based on an interregional accounting framework and initial information of interregional ...
Canning, Patrick, Wang, Zhi
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Guest Editorial: Spatial demography in regional science. [PDF]

J Geogr Syst, 2021
Franklin RS, Poot J.
europepmc   +1 more source

Spatial embeddedness and firm performance: an empirical exploration of the effects of proximity on innovative and economic performance [PDF]

Recent theoretical developments in organisation science and regional economics have emphasised the importance of networks and geographical proximity for the performance of firms.
Meeus, Marius T.H., Oerlemans, Leon A.G.
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Współczesne studia regionalne – teoria i metodologia, a także praktyka

Studia Regionalne i Lokalne, 2004
Artykuł podejmuje próbę przekrojowego przedstawienia ewolucji sposobów definiowania i opisu regionów, wskazując na ich wzajemne wynikanie oraz logiczne następstwo kolejnych analitycznych koncepcji regionu.
Iwona Sagan
doaj  

Latin American Network for Scientific Culture (RedLCC): A Regional Science Communication Initiative. [PDF]

Front Res Metr Anal, 2021
Moronta-Barrios F, Vargas-Domínguez S, Nuesch-Germano M, Torres V, Selvaggi K, Di Prinzio C, O'Brien E, Hernandez V, Monteiro M.   +8 more
europepmc   +1 more source