Results 71 to 80 of about 91,503 (308)
Regional service delivery among Pacific Island countries: an assessment [PDF]
, 2014 Experience with pooling service delivery among Pacific Island countries has not met the optimistic expectations of advocates, finds this study. Abstract Pacific Island countries face a range of development challenges, including smallness, distance from
Matthew Dornan, Tess Newton Cain
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Sustainability is Important Part of the Identity in the Dimension of Regionalism Architecture [PDF]
, 2015 The objectives of this study is to find that sustainable is important part of the identity in the dimention of regionalism Architecture. By conducting a study of the relationship between sustainable architecture with identity dimensions of regionalism in
Hidayatun, Maria Immaculata +2 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Building Block versus Stumbling Block Debate of Regionalism: From the Perspective of Service Trade Liberalization in Asia [PDF]
When debating the pros and cons of economic regionalism, haven't we focused enough on trade in goods at the expense of services? This article argues that regionalism is certainly a building block, not a stumbling block to a multilateral trading system ...
Hamanaka, Shintaro
core
Managing Complexity and Uncertainty in Regional Governance Networks:A Critical Analysis of State Rescaling in England [PDF]
, 2014 Network management is viewed as a way of dealing with uncertainty in complex policy networks, but little is known about the types of network management strategies employed by regional actors to manage vertical and horizontal relations.
Ayres, Sarah A, Stafford, Ian M
core +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Comparative Regionalism - A New Research Agenda [PDF]
After the end of the Cold War, students of International Relations observed an expansion of inter-state activities at the regional level. Regional and sub-regional groupings appeared to gain momentum as the way in which countries cooperate and should ...
Tanja A. Börzel
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source