Results 71 to 80 of about 92,548 (306)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The opening–dependence on the European Union and globalization [PDF]

open access: yes
Globalization is the result, as well as the cause of the expansion of trade agreements and liberalization of capital flows. Regionalism is a side effect of globalization, of particular importance in EU.
Sorica Sava
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Building Block versus Stumbling Block Debate of Regionalism: From the Perspective of Service Trade Liberalization in Asia [PDF]

open access: yes
When debating the pros and cons of economic regionalism, haven't we focused enough on trade in goods at the expense of services? This article argues that regionalism is certainly a building block, not a stumbling block to a multilateral trading system ...
Hamanaka, Shintaro
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

The Dynamics of the New and Open Regionalism and Economic Integration in Asia and the Pacific Regions

open access: yesExpert Journal of Business and Management, 2023
The purpose of the study reviewed the dynamics of new and open regionalism in Asia and the Pacific regions. It was highlighted that both in the Asia Pacific and Latin America, there is considerable confusion and ambiguity surrounding the notion of what ...
Andrew ENAIFOGHE, Trisha RAMSURAJ
doaj  

Comparative Regionalism - A New Research Agenda [PDF]

open access: yes
After the end of the Cold War, students of International Relations observed an expansion of inter-state activities at the regional level. Regional and sub-regional groupings appeared to gain momentum as the way in which countries cooperate and should ...
Tanja A. Börzel
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The ASEAN Way of Making Regionalism Work Beyond Five Decades: Processes, Remodelling and transformation

open access: yesMalaysian Journal of International Relations, 2017
The Association of Southeast Asian Nations (ASEAN) has reached its five decades of existence and expansion. While it has several limitations as a regional organisation, its lustre both from within and outside the region seems to have increased in recent ...
K. S. Balakrishnan
doaj   +1 more source

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