Results 61 to 70 of about 18,114 (265)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Delimitation of landscape units treated as estimation fields in the modelling of a landscape system

Miscellanea Geographica: Regional Studies on Development, 2013
The main objective of this paper is to represent the hierarchical structure of an environment by using two concepts: typology and regionalization. The Płock Region (1,766.95 sq. km) and transect crossing this area (796.2 sq. km) is the research location.
Richling Andrzej, Malinowska Ewa, Szumacher Iwona   +2 more
doaj   +1 more source

CLIMATE REGIONALIZATION OF SERBIA ACCORDING TO KÖPPEN CLIMATE CLASSIFICATION

Zbornik Radova: Geografski institut "Jovan Cvijić", 2017
The paper presents a concise overview of the theoretical framework on which climate classifications are based. Beside short review of climate classifications, namely climatic regionalization for Serbia (or wider area including Serbia), main deficiency of
Boško Milovanović, Vladan Ducić, Milan Radovanović, Milovan Milivojević   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Pacific Rim: Region or regions?

Papers of the Regional Science Association, 1990
Given the dynamic nature of the Pacific Rim, the Pacific Regional Science Conference Organization (PRSCO) has a unique opportunity to both grow with the region and contribute solutions to the problems which come with growth. This paper first examines some of the economic attributes of the Pacific Region and then explores some of the challenges and ...
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regionalization and continuing globalization scenarios as a result of re-globalization: a matter of ally-familiarity proximity in multiplex financial network

Applied Network Science
Some aspects of re-globalization were already fragmentary analyzed empirically in globalization and regionalization related research after the global financial crisis. These empirical studies suggest that re-globalization in terms of structural financial
Otilija Jurakovaite, Asta Gaigaliene
doaj   +1 more source