Results 131 to 140 of about 3,554,144 (293)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Associations between insomnia and pregnancy and perinatal outcomes: Evidence from mendelian randomization and multivariable regression analyses. [PDF]

PLoS Med, 2022
Yang Q, Borges MC, Sanderson E, Magnus MC, Kilpi F, Collings PJ, Soares AL, West J, Magnus P, Wright J, Håberg SE, Tilling K, Lawlor DA.   +12 more
europepmc   +1 more source

Understanding linear and logistic regression analyses [PDF]

CJEM, 2007
Andrew, Worster, Jerome, Fan, Afisi, Ismaila   +2 more
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Bayesian Analyses of Ridge Regression Prooblems

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
   A Bayesian formulation of the ridge regression problem is considerd, which derives from a direct specification of prior informations about parameters of general linear regression model when data suffer from a high degree of multicollinearity.A new ...
H. M. Gorgees
doaj  

Characterizing trends and associations for hepatitis C virus antibody prevalence in the Middle East and North Africa: meta-regression analyses. [PDF]

Sci Rep, 2022
Mahmud S, Chemaitelly H, Alaama AS, Hermez JG, Abu-Raddad LJ.   +4 more
europepmc   +1 more source

How well does brand personality predict brand choice ? [PDF]

The research proposes a methodology allowing both the construction of a brand personality scale and the test of the ability of the scale to predict brand choice. A brand personality scale is developed and tested via exploratory and confirmatory analyses.
Diwght Merunka, Jean-Marc Ferrandi, Laure Ambroise, Pierre Valette-Florence   +3 more
core  

Collapsible Kernel Machine Regression for Exposomic Analyses

Statistics in Medicine
ABSTRACT An important goal of environmental epidemiology is to quantify the complex health effects posed by a wide array of environmental exposures. In studies of a small number of exposures, flexible models like Bayesian kernel machine regression (BKMR) are appealing because they allow for non‐linear and non‐additive associations ...
Glen McGee, Brent A. Coull, Ander Wilson
openaire   +3 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source