Results 121 to 130 of about 2,842,066 (337)

BODY MASS INDEX AND EFFECTS DURING KAYAKING [PDF]

open access: yesSport Mont, 2012
Comparison of the results was performed among the sample of 55 male students of second year from the Faculty of Physical Education and Sports at the University of East Sarajevo, School Year 2009/2010, chronologically aged 23 years ±6 months.
Milomir Trivun   +3 more
doaj  

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Linear Discriminant Regularized Regression [PDF]

open access: yesarXiv
Linear Discriminant Analysis (LDA) is an important classification approach. Its simple linear form makes it easy to interpret and it is capable to handle multi-class responses. It is closely related to other classical multivariate statistical techniques, such as Fisher's discriminant analysis, canonical correlation analysis and linear regression.
arxiv  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Private Linear Regression with Differential Privacy and PAC Privacy [PDF]

open access: yesarXiv
Linear regression is a fundamental tool for statistical analysis, which has motivated the development of linear regression methods that satisfy provable privacy guarantees so that the learned model reveals little about any one data point used to construct it.
arxiv  

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

Logistic regression in the analysis of unexpected household expenses: Cross-country evidence

open access: yesJournal of International Studies, 2020
Patrycja Kowalczyk-Rólczyńska   +1 more
doaj   +1 more source

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