Results 51 to 60 of about 3,861,847 (314)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Comparison of the regression equations between AGB and SOC_NDVI.

, 2020
Comparison of the regression equations between AGB and SOC_NDVI.
Xiuli Chen (384084), Meirong Tian (703644), Jianjun Ma (158111), Yongjun Fan (6948806), Danlu Xing (8506812), Xiaohua Zhang (350570)   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Effect of average diurnal barn airspace temperatures on prediction of their development during the day

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011
A year-round (i.e. 365 days) experiment was performed at the Mendel University Training Farm in Žabčice, Czech Republic (GPS 49°0’51.967”N and 16°36’14.614”E, the altitude 179 m) with the aim to quantify the effect of the variation of average diurnal ...
Gustav Chládek, Oto Hanuš, Daniel Falta   +2 more
doaj   +1 more source

Scincidae regression equations and tests.

Sample sizes indicate number of extant scincid specimens that included the element used in the given regression. Regression equations are ranked in order of increasing standard error of the estimate (SEE).
Sara J. ElShafie (17743016)
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

ESTIMATING THE RESIDUAL OPERATING LIFE OF WOODEN STRUCTURES IN HIGH HUMIDITY CONDITIONS

Architecture and Engineering, 2020
Introduction: The paper addresses the issue of using regression equations to determine the residual operating life of structures made of wood of various species in high humidity conditions.
Aleksandr Chernykh, Dmitry Korolkov, Denis Nizhegorodtsev, Tatiana Kazakevich, Shirali Mamedov   +4 more
doaj   +1 more source

Anguidae regression equations and tests.

Sample sizes indicate number of extant anguid specimens that included the element used in the given regression. Regression equations are ranked in order of increasing standard error of the estimate (SEE).
Sara J. ElShafie (17743016)
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source