Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
On the inconsistency of the MLE in certain heteroskedastic regression models [PDF]
This paper studies the possibility of inconsistency of the maximum likelihood estimators for certain heteroskedastic regression models. These include the Poisson regression model and the ARCH models.
Adrián R. Pagan, Hernán Sabau
core
Simulation-informed kernel-based regression models for predicting temperature distribution in microwave hyperthermia. [PDF]
Alazwari MA, Abu-Hamdeh NH, Almitani KH.
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Sensitivity of machine learning regression models to data structure and quality in crop yield prediction. [PDF]
Zinzinhédo ML +3 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Stability and interpretability of penalized logistic regression models for breast cancer risk prediction. [PDF]
Okyere F, Nyanney M.
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Evaluating Geographically Weighted Regression Models for Environmental Chemical Risk Analysis
Jenna Czarnota +2 more
doaj
Interpretable Scalar-on-Image Linear Regression Models via the Generalized Dantzig Selector. [PDF]
Liao S, Sun X, Hao N, Zhang HH.
europepmc +1 more source

