Results 131 to 140 of about 2,020,990 (315)

Threshold regression with threg [PDF]

open access: yes
In this presentation, I introduce a new Stata command called threg. The command estimates regression coefficients of a threshold regression model based on the first hitting time of a boundary by the sample path of a Wiener diffusion process.
George A. Whitmore   +2 more
core  

Implementing PLS for distance-based regression: computational issues [PDF]

open access: yes, 2006
Distance-based regression allows for a neat implementation of the Partial Least Squares recurrence. In this paper we address practical issues arising when dealing with moderately large datasets (n ~ 10^4) such as those typical of automobile insurance ...
Boj, Eva   +4 more
core  

TBM Net Advance Rate Prediction Model Based on Ridge Regression Analysis

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Accurate prediction of TBM (tunnel boring machine) net advance rate is of significant reference value for selecting urban tunneling methods, planning construction schedules, and controlling construction costs.
SHI Jian   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Efficient Regression in Time Series Partial Linear Models [PDF]

open access: yes
This paper studies efficient estimation of partial linear regression in time series models. In particular, it combines two topics that have attracted a good deal of attention in econometrics, viz.
Peter C.B. Phillips   +2 more
core  

Multimodal Regression for Enzyme Turnover Rates Prediction

open access: yesCoRR
The enzyme turnover rate is a fundamental parameter in enzyme kinetics, reflecting the catalytic efficiency of enzymes. However, enzyme turnover rates remain scarce across most organisms due to the high cost and complexity of experimental measurements.
Bozhen Hu   +6 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Using Quantile Regression for Duration Analysis [PDF]

open access: yes
Quantile regression methods are emerging as a popular technique in econometrics and biometrics for exploring the distribution of duration data. This paper discusses quantile regression for duration analysis allowing for a flexible specification of the ...
Wilke, Ralf A., Fitzenberger, Bernd
core  

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