Results 31 to 40 of about 5,582,307 (290)
A full bayesian approach for boolean genetic network inference. [PDF]
PLoS ONE, 2014 Boolean networks are a simple but efficient model for describing gene regulatory systems. A number of algorithms have been proposed to infer Boolean networks.
Shengtong Han +5 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Mathematics, 2022 An alternative approach, known today as the Bernstein polynomials, to the Weierstrass uniform approximation theorem was provided by Bernstein. These basis polynomials have attained increasing momentum, especially in operator theory, integral equations ...
Faruk Özger +2 more
doaj +1 more source
Convergence of a regularization algorithm for nonexpansive and monotone operators in Hilbert spaces [PDF]
Fixed Point Theory and Applications, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yuan, Qing, Zhang, Yunpeng
openaire +2 more sources
Regular Convergence and Finite Element Methods for Eigenvalue Problems
, 2022 Regular convergence, together with various other types of convergence, has been studied since the 1970s for the discrete approximations of linear operators.
Sun, Jiguang, Gong, Bo
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Reconstruction of Higher-Order Differential Operators by Their Spectral Data
Mathematics, 2022 This paper is concerned with inverse spectral problems for higher-order (n>2) ordinary differential operators. We develop an approach to the reconstruction from the spectral data for a wide range of differential operators with either regular or ...
Natalia P. Bondarenko
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Discrete and Continuous Models and Applied Computational Science, 2020 The quasi-potential approach is very famous in modern relativistic particles physics. This approach is based on the so-called covariant single-time formulation of quantum field theory in which the dynamics of fields and particles is described on a space ...
Ilkizar V. Amirkhanov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source