Results 51 to 60 of about 89,950 (257)

A note on a generalization of injective modules

Karpatsʹkì Matematičnì Publìkacìï, 2020
As a proper generalization of injective modules in term of supplements, we say that a module $M$ has the property (ME) if, whenever $M\subseteq N$, $M$ has a supplement $K$ in $N$, where $K$ has a mutual supplement in $N$. In this study, we obtain that $(
B.N. Türkmen, E. Türkmen
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Annsemimaximal and Coannsemimaximal Modules

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
        Some authors studied modules with annihilator of every nonzero submodule is prime, primary or maximal. In this paper, we introduce and study annsemimaximal and coannsemimaximal modules, where an R-module M is called annsemimaximal (resp ...
I. M.A. Hadi, , H. Y. Khalaf
doaj  

FPGA-based network intrusion detection for IEC 61850-based industrial network

ICT Express, 2018
This paper proposes an FPGA-based network intrusion detection system for the IEC 61850-based industrial network that is specially designed for substation automation. The proposed system uses the Shift-And algorithm for detecting malicious network packets
Junsik Kim, Jaehyun Park
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Interactive E-module Based on H-Guided Inquiry: Optimize the ICT Skills and Learning Achievements

Berkala Ilmiah Pendidikan Fisika, 2020
This study aimed to optimize the ICT skills and the learning achievement of the students on the subject of the regular circular motion through the development of the interactive e-module that is based on the Hybrid Guided Inquiry with good criteria. As a
Nur Rohmah Utami, Akhmad Jufriadi, Hena Dian Ayu   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Simple modules over Auslander regular rings

Open Mathematics, 2017
In this paper, we discuss the properties of simple modules over Auslander regular rings with global dimension at most 3. Using grade theory, we show the right projective dimension of ExtΛ1(S,Λ)$\begin{array}{} \text{Ext}_{{\it\Lambda}}^{1}(S,\ {\it ...
Huang Chonghui, Zheng Lijing
doaj   +1 more source