Results 71 to 80 of about 89,950 (257)

The Cyclical Compactness in Banach C∞(Q)-Modules

Современная математика: Фундаментальные направления, 2019
In this paper, we study the class of laterally complete commutative unital regular algebras A over arbitrary fields. We introduce a notion of passport Γ(X) for a faithful regular laterally complete A- modules X, which consist of uniquely defined partition ...
V I Chilin, J A Karimov
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

On generalized morphic modules

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
Aim of the present article is to extend generalized morphic ring to modules. Let R be a commutative ring with a unity and M an R-module. M is said to be a generalized morphic module if for each m ∈ M, there exists a ∈ R such that annR (m) = (a) + annR (M
Çeken Seçil, Tekir Ünsal, Koç Suat
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

On n-flat modules and n-Von Neumann regular rings

International Journal of Mathematics and Mathematical Sciences, 2006
We show that each R-module is n-flat (resp., weakly n-flat) if and only if R is an (n,n−1)-ring (resp., a weakly (n,n−1)-ring). We also give a new characterization of n-Von Neumann regular rings and a characterization of weak n-Von Neumann regular rings ...
Najib Mahdou
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Some Results on W-regular Rings

NTU Journal of Pure Sciences
Von Neumann regular rings, introduced in 1936, form a cornerstone of abstract algebra and were later extended to weakly regular rings. This work considers another extension, the W-regular rings defined by Wei [6], and explores their properties and ...
Hazim Tallat Hazim
doaj   +1 more source

Virtually regular modules

Journal of Algebra and Its Applications
In this paper, we call a right module [Formula: see text] (strongly) virtually regular if every (finitely generated) cyclic submodule of [Formula: see text] is isomorphic to a direct summand of [Formula: see text]. [Formula: see text] is said to be completely virtually regular if every submodule of [Formula: see text] is virtually regular.
Engi̇n Büyükaşık, Özlem Irmak Demir   +1 more
openaire   +2 more sources