Results 71 to 80 of about 85,923 (255)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Cyclical Compactness in Banach C∞(Q)-Modules

Современная математика: Фундаментальные направления, 2019
In this paper, we study the class of laterally complete commutative unital regular algebras A over arbitrary fields. We introduce a notion of passport Γ(X) for a faithful regular laterally complete A- modules X, which consist of uniquely defined partition ...
V I Chilin, J A Karimov
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

On generalized morphic modules

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
Aim of the present article is to extend generalized morphic ring to modules. Let R be a commutative ring with a unity and M an R-module. M is said to be a generalized morphic module if for each m ∈ M, there exists a ∈ R such that annR (m) = (a) + annR (M
Çeken Seçil, Tekir Ünsal, Koç Suat
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

On n-flat modules and n-Von Neumann regular rings

International Journal of Mathematics and Mathematical Sciences, 2006
We show that each R-module is n-flat (resp., weakly n-flat) if and only if R is an (n,n−1)-ring (resp., a weakly (n,n−1)-ring). We also give a new characterization of n-Von Neumann regular rings and a characterization of weak n-Von Neumann regular rings ...
Najib Mahdou
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Some Results on W-regular Rings

NTU Journal of Pure Sciences
Von Neumann regular rings, introduced in 1936, form a cornerstone of abstract algebra and were later extended to weakly regular rings. This work considers another extension, the W-regular rings defined by Wei [6], and explores their properties and ...
Hazim Tallat Hazim
doaj   +1 more source