Results 111 to 120 of about 858,594 (303)

A tree crown edge-aware clipping algorithm for airborne LiDAR point clouds

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
Dividing a forest point cloud dataset into tiles is a common practice in point cloud processing (e.g., individual tree segmentation), aimed at addressing memory constraints and optimizing processing efficiency.
Shangshu Cai, Yong Pang
doaj   +1 more source

On the Proof Theory of Regular Fixed Points [PDF]

open access: yes, 2009
We consider encoding finite automata as least fixed points in a proof-theoretical framework equipped with a general induction scheme, and study automata inclusion in that setting. We provide a coinductive characterization of inclusion that yields a natural bridge to proof-theory.
openaire   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Reconstruction of industrial piping installations from laser point clouds using profiling techniques

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 143-152).As-built models of industrial piping installations are essential for planning applications in industry. Laser scanning has emerged as the preferred data acquisition method of as built
Mapurisa, Willard T
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

More about Divisible Design Graphs

open access: yes
: Divisible design graphs (DDG for short) have been recently defined by Kharaghani, Meulenberg and the second author as a generalization of (v, k, λ)-graphs.
Haemers, W.H., Crnkovic, D.
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Boundary partial Holder regularity for elliptic systems with non-standard growth

open access: yesElectronic Journal of Differential Equations, 2018
We investigate regular points on the boundaries of elliptic systems with non-standard growth, in particular, so-called Orlicz growth. A regular point on the boundary in this paper is a point for which a weak solution to a system is Holder continuous ...
Jihoon Ok
doaj  

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