Results 101 to 110 of about 858,594 (303)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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One-point compactifications and continuity for partial frames [PDF]
Categories and General Algebraic Structures with Applications, 2017 Locally compact Hausdorff spaces and their one-point compactifications are much used in topology and analysis; in lattice and domain theory, the notion of continuity captures the idea of local compactness.
John Frith, Anneliese Schauerte
doaj
Advances in Difference Equations, 2018 This paper introduces the regular decoupling field to study the existence and uniqueness of solutions of two-point boundary value problems for a class of ordinary differential equations which can be derived from the maximum principle in optimal control ...
Ruyi Liu, Zhen Wu
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Regularization techniques in interior point methods
Journal of Computational and Applied Mathematics, 2012 The author studies the factorization of the augmented system arising in interior point methods and generalizes the regularization techniques developed and used in linear programming to the case when the scaling matrix is positive semidefinite, but not diagonal.
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
SensorsTunnel point cloud semantic segmentation is a critical step in achieving refined perception and intelligent management of tunnel structures. Addressing common challenges including indistinct boundaries and fine-grained category discrimination, this paper
Junwei Tong +4 more
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HIDDEN REGULAR VARIATION FOR POINT PROCESSES AND THE SINGLE/MULTIPLE LARGE POINT HEURISTIC
, 2019 We consider regular variation for marked point processes with independent heavy-tailed marks and prove a single large point heuristic: the limit measure is concentrated on the cone of point measures with one single point.
Tillier, Charles +2 more
core
Convex Cone Conditions on the Structure of Designs [PDF]
, 2003 Various known and original inequalities concerning the structure of combinatorial designs are established using polyhedral cones generated by incidence matrices. This work begins by giving definitions and elementary facts concerning t-designs.
Dukes, Peter James
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source