Results 91 to 100 of about 858,594 (303)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Esters of ricebran oil with short chain alcohols as alternative fuel for diesel engines
Egyptian Journal of Petroleum, 2016 The potential of ricebran oil as a feedstock for the production of a fuel for diesel engines alternative to regular diesel fuel has been assessed. Esterification rate of crude ricebran oil with methyl alcohol was studied using different volumetric ratios
F.A. Zaher +3 more
doaj +1 more source
Trivial Jensen measures without regularity [PDF]
, 1999 In this note we construct Swiss cheeses X such that R(X) is non-regular but such that R(X) has no non-trivial Jensen measures. We also construct a non-regular uniform algebra with compact, metrizable character space such that every point of the character
Feinstein, Joel
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Concerns of middle and high school teachers toward inclusion of students with exceptional education needs [PDF]
, 2001 Plan BThe purpose of this study was to investigate the concerns of middle and high school regular education teachers in the West De Pere School District regarding inclusion of students with special needs into their general education classrooms.
Alexander, Jack
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Regular points for $\alpha $-harmonic functions
Hiroshima Mathematical Journal, 1983 A l'aide du critère de régularité de Wiener pour les potentiels de Riesz d'ordre \(\alpha ...
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Characterizations of Ordered Semigroups by New Type of Interval Valued Fuzzy Quasi-Ideals
Journal of Applied Mathematics, 2014 The concept of non-k-quasi-coincidence of an interval valued ordered fuzzy point with an interval valued fuzzy set is considered. In fact, this concept is a generalized concept of the non-k-quasi-coincidence of a fuzzy point with a fuzzy set.
Jian Tang, Xiangyun Xie, Yanfeng Luo
doaj +1 more source