Results 1 to 10 of about 6,082,428 (365)
Biological Research, 2023 Background Despite representing the largest fraction of animal life, the number of insect species whose genome has been sequenced is barely in the hundreds.
Sanae Kobayashi +32 more
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Canadian Respiratory Journal, 2022 Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading
Lan Wang +7 more
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BMC Medical Informatics and Decision Making, 2022 Background Smartphone technology can support paperless reporting of adverse drug reactions (ADRs). The aims of this study were to systematically assess smartphone ADR-reporting applications, understand their qualitative and quantitative impact on ADR ...
Ayako Fukushima +3 more
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Gene regulation by long non-coding RNAs and its biological functions
Nature reviews. Molecular cell biology, 2020 Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation. Recent studies have begun to unravel how the biogenesis of lncRNAs is distinct from that of mRNAs and is ...
Luisa Statello +3 more
semanticscholar +1 more source
Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences
Genome Biology, 2021 Background Animal genomes contain thousands of long noncoding RNA (lncRNA) genes, a growing subset of which are thought to be functionally important. This functionality is often mediated by short sequence elements scattered throughout the RNA sequence ...
Caroline Jane Ross +5 more
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GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch
Cell Communication and Signaling, 2022 Background G protein-coupled receptors (GPCRs) usually regulate cellular processes via activation of intracellular signaling pathways. However, we have previously shown that in several cell lines, GqPCRs induce immediate inactivation of the AKT pathway ...
Guy Nadel +9 more
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Argonaute—a database for gene regulation by mammalian microRNAs
BMC Bioinformatics, 2005 BackgroundThe Sulston score is a well-established, though approximate metric for probabilistically evaluating postulated clone overlaps in DNA fingerprint mapping.
Priyanka Shahi +9 more
semanticscholar +1 more source
PLK1 Signaling in Breast Cancer Cells Cooperates with Estrogen Receptor-Dependent Gene Transcription
Cell Reports, 2013 Polo-like kinase 1 (PLK1) is a key regulator of cell division and is overexpressed in many types of human cancers. Compared to its well-characterized role in mitosis, little is known about PLK1 functions in interphase.
Michael Wierer +6 more
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Scientific Reports, 2017 The anuran Rhinella spinulosa is distributed along the Andes Range at altitudes that undergo wide daily and seasonal variation in temperature. One of the populations inhabits geothermal streams, a stable environment that influences life history traits ...
Luis Pastenes +11 more
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Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice
Cell Journal, 2017 Objective Patients over 60 years of age have higher mortality and morbidity after major liver resections. Nitric oxide (NO) derived from the catalytic activity of Nos2 plays a beneficial role in liver regeneration (LR) after partial hepatectomy (PH). In
Deming Li +6 more
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