Results 21 to 30 of about 6,082,428 (365)
BMC Pulmonary Medicine, 2019 Background E-cigarette use prevalence has grown rapidly in the US. Despite the popularity of these products, few acute exposure toxicity studies exist, and studies on long-term pulmonary health effects are limited.
Albert D. Osei +8 more
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CK2 and PML: Regulating the Regulator [PDF]
Cell, 2006 The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transformation. In this issue of Cell, Scaglioni et al. (2006) show that phosphorylation of PML by CK2, a kinase frequently activated in human cancers, promotes PML degradation.
Lallemand-Breitenbach, V., de Thé, H.
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Cell Reports, 2014 The Wnt/β-catenin pathway and Nanog are key regulators of embryonic stem cell (ESC) pluripotency and the reprogramming of somatic cells. Here, we demonstrate that the repression of Dkk1 by Nanog, which leads indirectly to β-catenin activation, is ...
Lucia Marucci +5 more
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Nature Communications, 2020 Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao +11 more
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ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Genome Biology, 2021 Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships.
Yamile Márquez +7 more
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The regulators and the regulated [PDF]
Chemical & Engineering News Archive, 1983 It is far too early to make any final assessment of what has been happening at the Environmental Protection Agency these past few weeks. The resignation of Administrator Anne Burford and the firing of other senior agency officials are only the outward manifestations of the bigger issue of this Administration's attitude toward the environment.
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Intravital imaging of hair-cell development and regeneration in the zebrafish
Frontiers in Neuroanatomy, 2013 Direct videomicroscopic visualization of organ formation and regeneration in toto is a powerful strategy to study cellular processes that often cannot be replicated in vitro.
Hernan eLopez-Schier +5 more
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Metabolic regulation of gene expression by histone lactylation
Nature, 2019 The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells.
Di Zhang +23 more
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A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes
Genome Biology, 2017 Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown.
Hadas Hezroni +5 more
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Journal of Oral Microbiology, 2021 Introduction: Cystic fibrosis (CF) is an autosomal genetic disease, associated with the production of excessively thick mucosa and with life-threatening chronic lung infections. The microbiota of the oral cavity can act as a reservoir or as a barrier for
Jesse R. Willis +15 more
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