Results 171 to 180 of about 2,700,809 (357)

Regulatory architecture determines optimal regulation of gene expression in metabolic pathways [PDF]

, 2012
Victor Chubukov, Ignacio A. Zuleta, Hao Li   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Uncovering dynamic transcriptional regulation of methanogenesis via single-cell imaging of archaeal gene expression [PDF]

Yijing Dong, Qi Li, Fei Zhao, Yifan Chen, Lewen Liang, Jing Wang, Weishu Zhao, Fengping Wang, Heng Xu   +8 more
openalex   +1 more source

Foliar Application of Nahs Alleviates Cd Toxicity in Soybean Plants Through Regulation of Glutathione Metabolism and Gene Expression

, 2023
Hakimeh Oloumi, Mahmood Maleki, Leila Habibipour, Safa Lotfi   +3 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression. [PDF]

Nucleus, 2023
Tang Y.
europepmc   +1 more source

Generalized approach to the regulation and integration of gene expression [PDF]

, 2001
Jeong‐Il Oh, Samuel Kaplan
openalex   +1 more source

Autogenous regulation of gene expression [PDF]

Journal of Bacteriology, 1993
S, Maloy, V, Stewart
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source