Results 201 to 210 of about 1,659,012 (319)

The Molecular Biology of Dehydration Tolerance: Regulation of Gene Expression and Function in Xenopus Laevis

, 2020
Liam J. Hawkins
openalex   +2 more sources

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression [PDF]

, 2001
Satish Patel, Pamela A. Lochhead, Graham Rena, Calum Sutherland   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics. [PDF]

HGG Adv
Abe H, Lin P, Zhou D, Ruderfer DM, Gamazon ER.   +4 more
europepmc   +1 more source

Regulation of Alternative RNA Splicing by Exon Definition and Exon Sequences in Viral and Mammalian Gene Expression

, 2004
Zhi‐Ming Zheng
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell type and dynamic state govern genetic regulation of gene expression in heterogeneous differentiating cultures. [PDF]

Cell Genom
Popp JM, Rhodes K, Jangi R, Li M, Barr K, Tayeb K, Battle A, Gilad Y.   +7 more
europepmc   +1 more source

Glucocorticoid Regulation of Hepatic 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Gene Expression

, 1989
Alison Marker, Ann Colosia, Albert Tauler, David H. Solomon, Yvon E. Cayre, Aksel Lange, M. Raafat El‐Maghrabi, S.J. Pilkis   +7 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Small molecule-based regulation of gene expression in human astrocytes switching on and off the G-quadruplex control systems. [PDF]

J Biol Chem
M J VK, Mitteaux J, Wang Z, Wheeler E, Tandon N, Yun Jung S, Hudson RHE, Monchaud D, Tsvetkov AS.   +8 more
europepmc   +1 more source