Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Temporal regulation of gene expression during auxin-triggered crown root formation in barley: an integrated approach. [PDF]
Kořínková N +8 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research. [PDF]
Gebel J +8 more
europepmc +1 more source
Transcriptome analysis revealed enrichment pathways and regulation of gene expression associated with somatic embryogenesis in Camellia sinensis. [PDF]
Li HZ +12 more
europepmc +1 more source
Regulation of the sumoylation system in gene expression
Bin Liu, Ke Shuai
openalex +2 more sources
Differential Regulation of Starch-synthetic Gene Expression in Endosperm Between Indica and Japonica Rice Cultivars [PDF]
Tsuyoshi Inukai
openalex +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Toti: An integrated multi-omics database to decipher the epigenetic regulation of gene expression in totipotent stem cells. [PDF]
Chai Y +8 more
europepmc +1 more source

