Results 211 to 220 of about 4,210,615 (294)

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression. [PDF]

open access: yesNat Metab
Gates LA   +14 more
europepmc   +1 more source

Non-coding antisense transcripts: fine regulation of gene expression in cancer. [PDF]

open access: yesComput Struct Biotechnol J, 2022
Santos F   +4 more
europepmc   +1 more source

Regulation of human immunodeficiency virus env expression by the rev gene product [PDF]

open access: bronze, 1989
Marie‐Louise Hammarskjöld   +5 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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