Results 221 to 230 of about 2,700,809 (357)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Regulation of gene expression under high hydrostatic pressure: the versatile role of the master regulator SurR in energy metabolism. [PDF]

Front Microbiol
Moalic Y, Nguyen TBH, Hartunians J, Birien T, Thiel A, Jebbar M.   +5 more
europepmc   +1 more source

Behind the scenes: How RNA orchestrates the epigenetic regulation of gene expression. [PDF]

Front Cell Dev Biol, 2023
Mangiavacchi A, Morelli G, Orlando V.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Cross-kingdom regulation of gene expression in giant pandas via plant-derived miRNA. [PDF]

Front Vet Sci
Tan H, Wang C, Li F, Peng Y, Sima J, Li Y, Deng L, Wu K, Xu Z, Zhang Z.   +9 more
europepmc   +1 more source

Pan-Genomic Regulation of Gene Expression in Normal and Pathological Human Placentas. [PDF]

Cells, 2023
Apicella C, Ruano CSM, Thilaganathan B, Khalil A, Giorgione V, Gascoin G, Marcellin L, Gaspar C, Jacques S, Murdoch CE, Miralles F, Méhats C, Vaiman D.   +12 more
europepmc   +1 more source

Tissue-Specific Gene Expression and Regulation in Liver and Muscle following Chronic Corticosteroid Administration

, 2014
Tung Nguyen, Richard R. Almon, Debra C. DuBois, Siddharth Sukumaran, William J. Jusko, loannis P. Androulakis   +5 more
openalex   +1 more source

Cutting Edge: Progesterone Directly Upregulates Vitamin D Receptor Gene Expression for Efficient Regulation of T Cells by Calcitriol [PDF]

, 2014
Shankar Thangamani, Myughoo Kim, Youngmin Son, Xinxin Huang, Hee Joo Kim, Jee H. Lee, Jungyoon Cho, Benjamin J. Ulrich, Hal E. Broxmeyer, Chang H. Kim   +9 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Temporal regulation of gene expression through integration of p53 dynamics and modifications. [PDF]

Sci Adv
Lu D, Faizi M, Drown B, Simerzin A, François J, Bradshaw G, Kelleher N, Jambhekar A, Gunawardena J, Lahav G.   +9 more
europepmc   +1 more source