Results 221 to 230 of about 4,210,615 (294)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Transcription Factor Regulation of Gene Expression Network by ZNF385D and HAND2 in Carotid Atherosclerosis. [PDF]

Genes (Basel)
Tan M, Andersen LJ, Bruun NE, Lindholm MG, Tan Q, Snoer M.   +5 more
europepmc   +1 more source

Cognitive- and memory-enhancing effects of Augmentin in Alzheimer's rats through regulation of gene expression and neuronal cell apoptosis. [PDF]

Front Pharmacol, 2023
Kandeel M, Morsy MA, Abd El-Lateef HM, Marzok M, El-Beltagi HS, Al Khodair KM, Albokhadaim I, Venugopala KN.   +7 more
europepmc   +1 more source

Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle.

, 1986
R. Sanders Williams, Stanley Salmons, Eric A. Newsholme, Russel E. Kaufman, Jane Mellor   +4 more
openalex   +1 more source

Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila. [PDF]

, 1987
Manfred Frasch, Michael Levine
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Accounting for isoform expression increases power to identify genetic regulation of gene expression. [PDF]

PLoS Comput Biol
LaPierre N, Pimentel H.
europepmc   +1 more source

The Tissue-specific Expression and Developmental Regulation of Two Nuclear Genes Encoding Rat Mitochondrial Proteins

, 1989
Daniel P. Kelly, Jeffrey I. Gordon, R Alpers, Arnold W. Strauss   +3 more
openalex   +1 more source

Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. [PDF]

, 1987
Robert C. Fuhlbrigge, David Chaplin, Jeanne-Marie Kíely, Emil R. Unanue   +3 more
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source