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Regulation Of Neuropeptide Gene Expression

Annual Review of Neuroscience, 1990
Understanding of the mechanisms of neuropeptide gene regulation has increased dramatically in the past 5 years. In large part, this increased understanding has resulted from advances in the technology of introducing reporter genes into intact cells in culture.
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Regulation of Gene Expression by Glucocorticoids

Annual Review of Physiology, 1989
Steroid hormones mediate profound physiological and developmental effects in higher eukaryotes. By interacting with their intracellular receptors in target cells, steroid hormones provide mechanisms for cellular communication and alterations in phenotypic response to environmental and internal stimuli.
K L, Burnstein, J A, Cidlowski
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Regulating gene expression in gene therapy

Trends in Biotechnology, 1993
Ensuring that expression of introduced genes is both safe and effective necessitates directing expression to the appropriate tissue, at levels which produce a therapeutic effect. Extensive research is under way to elucidate the mechanisms and genetic elements involved in regulating expression. With the need to correlate expression levels and phenotypic
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Osmotic regulation of gene expression

The FASEB Journal, 1996
Cells react to increased osmolality with numerous changes in gene expression. The specific genes affected differ between species, but the known osmoprotective effects of the gene products are remarkably similar, particularly with regard to cellular accumulation of compatible organic os‐ molytes. Here we concentrate on the molecular
M B, Burg, E D, Kwon, D, Kültz
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Regulation of KiSS1 gene expression

Peptides, 2009
Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood.
Dali, Li, Weishi, Yu, Mingyao, Liu
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Biotin — a regulator of gene expression

The Journal of Nutritional Biochemistry, 2005
The role of biotin as the prosthetic group of the four biotin-dependent carboxylases in higher organisms is well recognized. Based on the roles of these carboxylases in metabolism, the requirement of biotin for cell viability, growth and differentiation was established. Biotin seems to have a role in cell functions other than as the prosthetic group of
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Regulation of opioid gene expression

Peptides, 1983
Opioid peptides are synthesized in the form of large precursors, which contain the information for more than one biologically active peptide. Using recombinant DNA technology, three opioid precursors have been sequenced: pro-opiomelanocortin (POMC), proenkephalin and prodynorphin.
O, Civelli   +6 more
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Regulation of metallothionein gene expression

2000
The rapid and robust induction of metallothioneins (MT)-I and II by a variety of inducers that include heavy toxic metals, reactive oxygen species, and different types of stress provide a useful system to study the molecular mechanisms of this unique induction process.
K, Ghoshal, S T, Jacob
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Regulation of histone gene expression

Current Opinion in Cell Biology, 1992
Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory ...
Stein, Gary S.   +3 more
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Ploidy Regulation of Gene Expression

Science, 1999
Microarray-based gene expression analysis identified genes showing ploidy-dependent expression in isogenic Saccharomyces cerevisiae strains that varied in ploidy from haploid to tetraploid. These genes were induced or repressed in proportion to the number of chromosome sets, regardless of the mating type.
T, Galitski   +4 more
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