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Mitochondrial OXPHOS restricts SARS-CoV-2 replication. [PDF]

open access: yesSci Adv
Soto Albrecht YE   +21 more
europepmc   +1 more source

Epitranscriptomic regulation of viral replication

open access: yesBiochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2017
RNA plays central roles in biology and novel functions and regulation mechanisms are constantly emerging. To accomplish some of their functions within the cell, RNA molecules undergo hundreds of chemical modifications from which N6-methyladenosine (m6A), inosine (I), pseudouridine (ψ) and 5-methylcytosine (5mC) have been described in eukaryotic mRNA ...
Fernando Valiente-Echeverría   +1 more
exaly   +4 more sources

HSV-1 DNA Replication—Coordinated Regulation by Viral and Cellular Factors [PDF]

open access: yesViruses, 2021
DNA replication is an integral step in the herpes simplex virus type 1 (HSV-1) life cycle that is coordinated with the cellular DNA damage response, repair and recombination of the viral genome, and viral gene transcription. HSV-1 encodes its own DNA replication machinery, including an origin binding protein (UL9), single-stranded DNA binding protein ...
Jill Dembowski
exaly   +4 more sources
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MicroRNA regulation of viral replication in teleost fish: a review

Reviews in Aquaculture, 2021
AbstractMicroRNAs (miRNAs) are single‐stranded non‐coding RNA molecules. In addition to participating in various biological processes of eukaryotes, such as cell proliferation, development, differentiation, metabolism, tumorigenesis, and apoptosis, miRNAs also play an important role in the regulation of virus replication.
Jiagang Tu, Yong-An Zhang
exaly   +2 more sources

Molecular mechanisms of PI4K regulation and their involvement in viral replication

Traffic, 2022
AbstractLipid phosphoinositides are master signaling molecules in eukaryotic cells and key markers of organelle identity. Because of these important roles, the kinases and phosphatases that generate phosphoinositides must be tightly regulated. Viruses can manipulate this regulation, with the Type III phosphatidylinositol 4‐kinases (PI4KA and PI4KB ...
Jacob A. McPhail, John E. Burke
openaire   +2 more sources

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