Results 221 to 230 of about 183,339 (262)

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

ZBP1 as a dynamic monitor of viral replication: implications for therapeutic strategies. [PDF]

open access: yesFront Cell Infect Microbiol
Ou Z   +5 more
europepmc   +1 more source

Hypoxia inducible factors regulate pneumovirus replication by enhancing innate immune sensing. [PDF]

open access: yesProc Natl Acad Sci U S A
Ha J   +15 more
europepmc   +1 more source

MicroRNA regulation of viral replication in teleost fish: a review

Reviews in Aquaculture, 2021
AbstractMicroRNAs (miRNAs) are single‐stranded non‐coding RNA molecules. In addition to participating in various biological processes of eukaryotes, such as cell proliferation, development, differentiation, metabolism, tumorigenesis, and apoptosis, miRNAs also play an important role in the regulation of virus replication.
Chi Zhang, Jiagang Tu, Yong‐An Zhang
openaire   +1 more source

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