Results 81 to 90 of about 6,497,314 (414)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
First Report of Fishkill Incidence in Bonny-Andoni Coastal Area, Nigeria
Croatian Journal of Fisheries, 2023 A fish kill is characterised by the death of a large number of fish in a given area within a short period of time. This is an indicator that water quality and ecosystem conditions in general have deteriorated.
Chukwuka Azubuike Victor
doaj +1 more source
arXiv, 2017 Among recently introduced new notions in real algebraic geometry is that of regulous functions. Such functions form a foundation for the development of regulous geometry. Several interesting results on regulous varieties and regulous sheaves are already available. In this paper, we define and investigate regulous vector bundles.
arxiv
PLoS ONE, 2015 Objective To review existing regulations and policies utilised by countries to enable patient access to orphan drugs. Methods A review of the literature (1998 to 2014) was performed to identify relevant, peer-reviewed articles. Using content analysis, we
T. Gammie, Christine Y. Lu, Z. Babar
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
How does the alcohol industry attempt to influence marketing regulations? A systematic review
Addiction, 2015 Aim To systematically review, using a qualitative, narrative synthesis approach, papers examining alcohol industry efforts to influence alcohol marketing policy, and compare with those used by the tobacco industry.
Emily Savell, G. Fooks, A. Gilmore
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Does Collective Genetic Regulation exist? [PDF]
arXiv, 2021 Does regulation in the genome use collective behavior, similar to the way the brain or deep neural networks operate? Here I make the case for why having a genomic network capable of a high level of computation would be strongly selected for, and suggest how it might arise from biochemical processes that succeed in regulating in a collective manner ...
arxiv
Examples of State Flexible Work Arrangement (FWA) Laws [PDF]
, 2006 Flexible Work Arrangements (FWAs) alter the time and/or place that work is conducted on a regular basis -- in a manner that is as manageable and predictable as possible for both employees and employers.
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
Regulations and robust low-carbon buildings [PDF]
, 2009 Building regulations and associated calculation methods have been rapidly evolving, driven in Europe by the European Union Energy Performance of Buildings Directive. As an example, the current UK regulations are explored in relation to buildings that are
Tuohy, Paul
core +1 more source