Results 211 to 220 of about 449,254 (259)

NAT10 as a central node in cancer biology: integrating epitranscriptomic regulation, metabolic reprogramming, and immune modulation. [PDF]

Front Immunol
Bo W, Yi Y, Zhao B, Dong H.
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Evolutionary Genomics of Human Gut Bacteria: Ecological Plasticity Across the Mutualism-Pathogenicity Spectrum. [PDF]

Int J Mol Sci
Ramadan YN, Bukhari SQ, Alatawi Z, Oriquat G, Ellah NHA, Mohamedosman EHA, Ahmed R, Hetta HF.   +7 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

From Epigenetic Dysregulation to Therapeutic Reprogramming in Endometrial Cancer: A State-Response Framework for Treatment Resistance. [PDF]

Int J Mol Sci
Srivastava M, Singh S, Kumar P, Moond N, Chouhan A, Mann K, Kumari S, Banerjee M, Kushwah AS.   +8 more
europepmc   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Advances in molecular innate immune regulation in the development and therapeutic strategies of allergic rhinitis vaccines. [PDF]

Front Immunol
Liu Y, Meng C, Sha J, Zhu D, Sun Q, Wu N.   +5 more
europepmc   +1 more source

Immunopathogenesis and immunoregulatory mechanisms in allergic contact dermatitis. [PDF]

Front Immunol
Tong Y, Chen H, Kou Q, He B, Tang Y, Ran K, Zhang L, Gan X.   +7 more
europepmc   +1 more source

Special Issue "Current Research on the Role of the Gut Microbiota in Human Diseases and Health". [PDF]

Int J Mol Sci
Cretoiu SM.
europepmc   +1 more source

Adolescence and young adulthood: a critical period for lifelong health. [PDF]

Korean J Fam Med
Jeong SM.
europepmc   +1 more source