Results 171 to 180 of about 6,202,519 (294)

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Science, 2011
K. Atarashi, Takeshi Tanoue, T. Shima, A. Imaoka, T. Kuwahara, Y. Momose, G. Cheng, S. Yamasaki, T. Saito, Y. Ohba, T. Taniguchi, K. Takeda, S. Hori, I. Ivanov, Y. Umesaki, K. Itoh, K. Honda   +16 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Global Pharmaceutical Regulation: Comparative Frameworks and Operations. [PDF]

Pharmacy (Basel)
Umaru OT, Adeyemi AS, Aderonmu O, Bhangu BS, Dhaliwal HS, Lim H, Aremu TO.   +6 more
europepmc   +1 more source

EU financial regulatory reform: a status report [PDF]

In this paper, Nicolas Véron argues that the EU regulatory response to the crisis has been generally slower in the EU than in the United States, for four main reasons: swifter financial crisis management and resolution in the US; structural differences ...
Nicolas Véron
core   +1 more source

The nature of procrastination: a meta-analytic and theoretical review of quintessential self-regulatory failure.

Psychological bulletin, 2007
Piers Steel
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Post-Incident Assessment Cognitive Analysis in Facility Catastrophes

Platform, a Journal of Engineering
This study uses a cognitive method to analyse a judgement support system and assessment strategy for the aftereffects of a catastrophic facility.
Hasnolizar Zakaria, Masdi Muhammad
doaj  

Assessing regulatory institutions and building collapse in Lagos state, Nigeria. [PDF]

Sci Rep
Salau WO, Anifowose RK.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Federating AI-related regulations for human therapeutics: an AI-enabled, continuously updating regulatory intelligence system. [PDF]

Front Drug Saf Regul
Singh R, Pareek M, Prokle M, Sanchez E, Hohgrawe U, Auclair JR.   +5 more
europepmc   +1 more source