Results 151 to 160 of about 5,141,166 (402)
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Reconstructing Climate Policy: Beyond Kyoto [PDF]
, 2003 In their comprehensive analysis of the Kyoto Protocol and climate policy, Richard B. Stewart and Jonathan B. Wiener examine the current impasse in climate policy and the potential steps nations can take to reduce greenhouse gases.
Stewart, Richard B., Wiener, Jonathan B.
core +2 more sources
Presence of transcription regulatory elements within an intron of the virus-inducible murine TIMP gene. [PDF]
, 1988 Benoit Coulombe +4 more
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Genes & Development, 2017 Here, Erceg et al. studied the occupancy of the Drosophila PhoRC during embryogenesis and revealed extensive co-occupancy at developmental enhancers. By using an established in vivo assay for Polycomb response element (PRE) activity, they show that a ...
Jelena Erceg +6 more
semanticscholar +1 more source
Computational genomics of regulatory elements and regulatory territories
, 2017 Whole genome comparison of metazoan genomes reveals extremely high level of noncoding conservation over tens to hundreds of base pairs across distant species. These sequences are termed as conserved noncoding elements (CNEs). Arrays of conserved noncoding elements that span the loci of developmental regulatory genes and their span defines regulatory ...
openaire +4 more sources
Interfering contexts of regulatory sequence elements [PDF]
Bioinformatics, 1996 Although one would normally expect a given regulatory element to perform best when it fully matches its consensus sequence, this is generally far from being the case. Usually, almost none of the actual sites fits the consensus exactly, and some of those that do fit do not perform well.
openaire +3 more sources
The Gate-Resonance Model - The interface of policy, media and the public in technology conflicts [PDF]
The gate/resonance model provides an analytical frame for the description of technology conflicts. It offers an analytical scheme to conceptualise the interaction between public opinion, interest representing organisations, the media and the political ...
Helge Torgersen, Jürgen Hampel
core
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Regulatory elements involved in Drosophila Adh gene expression are conserved in divergent species and separate elements mediate expression in different tissues. [PDF]
, 1986 Janice A. Fischer, Tom Maniatis
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