Results 341 to 350 of about 5,141,166 (402)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Machine-guided design of cell-type-targeting cis-regulatory elements. [PDF]

Nature
Gosai SJ, Castro RI, Fuentes N, Butts JC, Mouri K, Alasoadura M, Kales S, Nguyen TTL, Noche RR, Rao AS, Joy MT, Sabeti PC, Reilly SK, Tewhey R.   +13 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Convergent Degenerated Regulatory Elements Associated with Limb Loss in Limbless Amphibians and Reptiles. [PDF]

Mol Biol Evol
Zhu C, Li S, Zhang D, Zhang J, Wang G, Zhou B, Zheng J, Xu W, Wang Z, Gao X, Liu Q, Xue T, Zhang H, Li C, Ge B, Liu Y, Qiu Q, Zhang H, Huang J, Tang B, Wang K.   +20 more
europepmc   +1 more source

Epigenomic identification of vernalization cis-regulatory elements in winter wheat. [PDF]

Genome Biol
Liu Y, Liu P, Gao L, Li Y, Ren X, Jia J, Wang L, Zheng X, Tong Y, Pei H, Lu Z.   +10 more
europepmc   +1 more source

G-quadruplexes as pivotal components of cis-regulatory elements in the human genome. [PDF]

BMC Biol
Zhang R, Wang Y, Wang C, Sun X, Mergny JL.   +4 more
europepmc   +1 more source

TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact. [PDF]

NPJ Genom Med
Canson DM, Llinares-Burguet I, Fortuno C, Sanoguera-Miralles L, Bueno-Martínez E, de la Hoya M, Spurdle AB, Velasco-Sampedro EA.   +7 more
europepmc   +1 more source

Genome-Wide Identification and Characterization of the <i>WRKY</i> Gene Family and Their Associated Regulatory Elements in <i>Fortunella hindsii</i>. [PDF]

Evol Bioinform Online
Hussain H, Alam A, Mehar I, Noor M, Al-Dossary O, Alsubaie B, Al-Mssallem MQ, Al-Khayri JM.   +7 more
europepmc   +1 more source

Capturing cell-type-specific activities of cis-regulatory elements from peak-based single-cell ATAC-seq. [PDF]

Cell Genom
Chen M.
europepmc   +1 more source