Results 351 to 360 of about 5,375,401 (399)

The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements

Koulle A, Ogundele O, Shah D, Baker I, Lopez M, Reynolds N, Ragheb R, Laue E, Hendrich B.   +8 more
europepmc   +1 more source

Deciphering cis-regulatory elements using REgulamentary

Riva SG, Georgiades E, Herrmann JC, Gür ER, Sanders E, Sergeant M, Baxter M, Hughes JR.   +7 more
europepmc   +1 more source

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Determinants of enhancer and promoter activities of regulatory elements

Nature Reviews Genetics, 2019
Robin Andersson, Albin Sandelin
exaly   +2 more sources

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites

Science, 2023
Understanding the regulatory landscape of the human genome is a long-standing objective of modern biology. Using the reference-free alignment across 241 mammalian genomes produced by the Zoonomia Consortium, we charted evolutionary trajectories for 0.92 ...
Gregory Andrews, K. Fan, H. Pratt, Nishigandha Phalke, E. Karlsson, K. Lindblad-Toh, S. Gazal, Jill E. Moore, Z. Weng, Gregory Andrews, Joel C. Armstrong, M. Bianchi, B. Birren, K. Bredemeyer, Ana M. Breit, M. Christmas, H. Clawson, Joana Damas, F. Di Palma, M. Diekhans, Michael X. Dong, E. Eizirik, K. Fan, Cornelia Fanter, Nicole M. Foley, K. Forsberg-Nilsson, Carlos J. Garcia, J. Gatesy, S. Gazal, D. Genereux, Linda Goodman, Jenna R. Grimshaw, Michaela K. Halsey, Andrew J. Harris, G. Hickey, Michael Hiller, Allyson Hindle, R. Hubley, Graham M. Hughes, Jeremy Johnson, David Juan, Irene M. Kaplow, E. Karlsson, Kathleen C. Keough, B. Kirilenko, Klaus‐Peter Koepfli, Jennifer M. Korstian, Amanda Kowalczyk, S. Kozyrev, Alyssa J. Lawler, C. Lawless, T. Lehmann, D. Levesque, H. Lewin, Xue Li, Abigail L. Lind, K. Lindblad-Toh, Ava Mackay-Smith, Voichita D. Marinescu, Tomàs Marquès-Bonet, Victor C. Mason, J. Meadows, Wynn K. Meyer, Jill E. Moore, L. R. Moreira, Diana D. Moreno-Santillán, Kathleen Morrill, G. Muntané, W. Murphy, A. Navarro, M. Nweeia, S. Ortmann, Austin B. Osmanski, B. Paten, Nicole S. Paulat, Andreas R. Pfenning, BaDoi N. Phan, K. Pollard, H. Pratt, D. Ray, Steven K. Reilly, Jeb Rosen, I. Ruf, Louise Ryan, Oliver A. Ryder, Pardis C Sabeti, Daniel E. Schäffer, Aitor Serres, B. Shapiro, Arian F. A. Smit, M. Springer, Chaitanya Srinivasan, C. Steiner, Jessica M. Storer, Kevin A. M. Sullivan, P. Sullivan, E. Sundström, Megan A. Supple, Ross Swofford, Joy-El R B Talbot, E. Teeling, Jason Turner-Maier, A. Valenzuela, Franziska Wagner, Ola Wallerman, Chao Wang, Juehan Wang, Z. Weng, Aryn P. Wilder, Morgan E. Wirthlin, James R. Xue, Xiaomeng Zhang   +111 more
semanticscholar   +1 more source

Mapping regulatory elements

Nature Biotechnology, 2016
Regulatory genomic elements can now be studied in their native context using two CRISPR-based high-throughput approaches.
Yuexin, Zhou, Wensheng, Wei
openaire   +2 more sources

Erythroid regulatory elements

STEM CELLS, 1993
Erythroid differentiation leads to the production of red blood cells that contain a high level of hemoglobin. This level is mainly regulated by globin gene transcription during development and differentiation. Although numerous cis-acting sequences are involved in transcriptional activity of globin genes, combinations of three motifs, CCACC, SP1 and ...
N, Raich, P H, Romeo
openaire   +2 more sources

Regulatory elements in aflatoxin biosynthesis

Mycotoxin Research, 2006
This review provides a synopsis of factors involved in the regulation of aflatoxin inAspergillus species at the molecular level. Much of the knowledge available today on the regulation of secondary metabolite production in fungi has been gleaned from studies of the aflatoxin gene cluster inA. flavus andA.
J W, Cary, K C, Ehrlich, S P, Kale, A M, Calvo, D, Bhatnagar, T E, Cleveland   +5 more
openaire   +2 more sources

Conserved regulatory elements in AMPK

Nature, 2013
arising from B. Xiao et al. , 230–233 (2011)10.1038/nature09932 The AMP-activated protein kinase (AMPK), an αβγ heterotrimeric enzyme, has a central role in regulating cellular metabolism and energy homeostasis1.
Chen, Lei, Xin, Feng-Jiao, Wang, Jue, Hu, Jicheng, Zhang, Yuan-Yuan, Wan, Shuo, Cao, Lu-Sha, Lu, Chang, Li, Peng, Yan, S. Frank, Neumann, Dietbert, Schlattner, Uwe, Xia, Bin, Wang, Zhi-Xin, Wu, Jia-Wei   +14 more
openaire   +3 more sources

REGULATORY ELEMENTS OF MARINE CYANOBACTERIA

Genome Informatics 2007, 2007
The free-living, oxyphototroph bacteria of the group of Prochlorococcus populate widely the oceans. Genomic information of nine marine cyanobacteria was used to predict signals essential for regulation. We implemented a pipeline that automatically calculates BLASTp alignments of query genomes, selects a representative subset of orthologs and predicts ...
Szymon M, Kiełbasa, Hanspeter, Herzel, Ilka M, Axmann   +2 more
openaire   +2 more sources

Massively parallel characterization of regulatory elements in the developing human cortex

Science
Nucleotide changes in gene regulatory elements are important determinants of neuronal development and diseases. Using massively parallel reporter assays in primary human cells from mid-gestation cortex and cerebral organoids, we interrogated the cis ...
Chengyu Deng, Sean Whalen, Marilyn R. Steyert, Ryan S. Ziffra, P. Przytycki, Fumitaka Inoue, Daniela A. Pereira, Davide Capauto, Scott Norton, F. Vaccarino, Alex A. Pollen, T. Nowakowski, N. Ahituv, K. Pollard   +13 more
semanticscholar   +1 more source