Results 261 to 270 of about 29,276,589 (300)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Achieving Public Health Impact: Health Communication Research to Inform Tobacco Regulatory Science. [PDF]

open access: yesHealth Commun
Noar SM   +5 more
europepmc   +1 more source

Regulatory science in Asia: current and future aspects of regulatory science in Korea

open access: yesAnnual Meeting of the Japanese Society of Toxicology, 2012
openaire   +1 more source
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Biomaterials and regulatory science

Journal of Materials Science and Technology, 2022
Xu Song, Antonios Mikos, Lei Yang
exaly   +2 more sources

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