Results 211 to 220 of about 2,996,073 (354)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Inhibition of estrogen receptor alpha stabilizes regulatory T cell function in autoimmune hepatitis. [PDF]

JHEP Rep
Zhang L, Gromova B, Nguyen DH, Cagle C, Gomes GS, Li W, Gao L, Zhang W, Graham JJ, Wang N, Kalbasi A, Csizmadia E, Wei A, Cassavaugh J, Bonder A, Patwardhan V, Jiang S, Kota SK, Longhi MS.   +18 more
europepmc   +1 more source

Th17: an effector CD4 T cell lineage with regulatory T cell ties.

Immunity, 2006
C. Weaver, L. Harrington, Paul R. Mangan, Maya Gavrieli, K. Murphy   +4 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The ionotropic AMPA receptor contributes to autoimmunity via altered regulatory T cell differentiation. [PDF]

iScience
Mitchell-Flack M, Higgins M, Zheng Y, Tam A, Goldschmidt H, Nishio H, Liu B, Cherry CM, Patatanian M, Blosser R, Mun SS, Suru A, Huganir R, Yu H, Pardoll D.   +14 more
europepmc   +1 more source

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.

Immunity, 2008
Y. Rubtsov, J. P. Rasmussen, E. Chi, J. Fontenot, L. Castelli, X. Ye, P. Treuting, Lisa Siewe, Axel Roers, W. Henderson, Werner Müller, A. Rudensky   +11 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The Potential of β-Synuclein-Specific Regulatory T Cell Therapy as a Treatment for Progressive Multiple Sclerosis. [PDF]

Int J Mol Sci
Osmond GE, John NA, Ting YT, Ooi JD.
europepmc   +1 more source

Low expression and hypermethylation of FOXP3 in regulatory T cells are associated with asthma in children

, 2020
Xiaohua Zhu, Qiang Chen, Zhiqiang Liu, Daya Luo, Lan Li, Ying Zhong   +5 more
openalex   +2 more sources

Molecular mechanisms of peripheral CD25 regulatory T cell (Treg) development [PDF]

, 2010
Iryna Prots, Alla Skapenko, P E Lipsky, Hendrik Schulze‐Koops   +3 more
openalex   +1 more source