Results 241 to 250 of about 2,996,073 (354)

Label-free estimation of regulatory T cell activation markers using Raman spectroscopy with machine learning. [PDF]

Sci Rep
Azari-Pour A, Chamkalani A, Rangan S, MacDonald KN, Huynh M, Levings MK, Schulze HG, Piret JM, Gopaluni B.   +8 more
europepmc   +1 more source

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

Nature Medicine, 2015
I. Mascanfroni, M. Takenaka, A. Yeste, B. Patel, Yan Wu, Jessica E. Kenison, S. Siddiqui, A. Basso, L. Otterbein, D. Pardoll, F. Pan, A. Priel, C. Clish, S. Robson, F. Quintana   +14 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Beyond the Classical Triad: Atypical Presentations and Regulatory T Cell Phenotyping in a Cohort of IPEX Patients. [PDF]

J Clin Immunol
Yaz I, Oskay Halacli S, Ipsir C, Ulum B, Soyak Aytekin E, Bildik HN, Ocak M, Avci H, Okur FV, Hizarcioglu Gulsen H, Demir H, Metin A, Ozon A, Kuskonmaz B, Tezcan I, Esenboga S, Cagdas D.   +16 more
europepmc   +1 more source

Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation

Mucosal Immunology, 2015
B.‐H. Yang, S. Hagemann, Panagiota Mamareli, Uta Lauer, U. Hoffmann, M. Beckstette, Lisa Föhse, I. Prinz, Joern Pezoldt, S. Suerbaum, T. Sparwasser, A. Hamann, S. Floess, J. Huehn, M. Lochner   +14 more
semanticscholar   +1 more source

Systemic Transplantation of Human Umbilical Cord Derived Mesenchymal Stem Cells-Educated T Regulatory Cells Improved the Impaired Cognition in AβPPswe/PS1dE9 Transgenic Mice

, 2013
Hongna Yang, Hui Yang, Zhaohong Xie, LiFei Wei, Jianzhong Bi   +4 more
openalex   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Bone Marrow Mesenchymal Stromal Cell Osteogenesis is driven by Paracrine signals from Regulatory T Cell. [PDF]

Stem Cell Rev Rep
Baysal E, Al-Sharabi N, Mustafa K, Costea DE, Brennan M, Suliman S.   +5 more
europepmc   +1 more source

The PI3K p110δ Regulates Expression of CD38 on Regulatory T Cells

, 2011
Daniel T. Patton, Marcus D. Wilson, Wendy C. Rowan, Dalya R. Soond, Klaus Okkenhaug   +4 more
openalex   +2 more sources

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source