Results 101 to 110 of about 196,068 (330)

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Optimizing TSCH Scheduling for IIoT Networks Using Reinforcement Learning

open access: yesTechnologies
In the context of industrial applications, ensuring medium access control is a fundamental challenge. Industrial IoT devices are resource-constrained and must guarantee reliable communication while reducing energy consumption. The IEEE 802.15.4e standard
Sahar Ben Yaala   +2 more
doaj   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

open access: yesAdvanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai   +6 more
wiley   +1 more source

Terapia por contingências de reforçamento: um estudo de caso sobre depressão infantil e "fala alucinatória"

open access: yesPsicologia, 2005
This case study report is an example of the therapeutic process based on Therapy by Contingencies of Reinforcement (TCR) conducted with Cacá, 12 years old, and her parents. The initial complaints involved depression, difficulties in social relations, and
Andréia Cláudia dos Santos Marianno   +1 more
doaj  

Increasing the Reinforcing Value of Exercise in Overweight Adults

open access: yesFrontiers in Behavioral Neuroscience, 2019
Objectives: This study determined whether a moderate- or high-dose exercise program increases exercise reinforcement. Increasing the relative reinforcing value of exercise (RRVexercise; i.e., incentive sensitization of exercise) may increase the usual ...
Kyle D. Flack   +3 more
doaj   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

open access: yesAdvanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang   +8 more
wiley   +1 more source

Therapy by Contingencies of Reinforcement: A Case Study about Child Depression and “Delusional Speech”

open access: yesPsicologia, 2005
This case study report is an example of the therapeutic process based on Therapy by Contingencies of Reinforcement (TCR) conducted with Cacá, 12 years old, and her parents. The initial complaints involved depression, difficulties in
Andréia Cláudia dos Santos Marianno   +1 more
doaj  

Effect of Schedule-Induced Behavior on Responses of Spontaneously Hypertensive and Wistar–Kyoto Rats in a Delay-Discounting Task: A Preliminary Report

open access: yesFrontiers in Behavioral Neuroscience, 2019
Delay discounting is the loss of the subjective value of an outcome as the time to its delivery increases. It has been suggested that organisms can become more tolerant of this delay when engaging in schedule-induced behaviors. Schedule-induced behaviors
Sergio Ramos   +4 more
doaj   +1 more source

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