Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS
Despite being an early event in ALS, it remains unclear whether the denervation of neuromuscular junctions (NMJ) is simply the first manifestation of a globally degenerating motor neuron.
Éric Martineau +3 more
doaj +1 more source
Safety, Tolerability, and Effect of Nusinersen Treatment in Ambulatory Adults With 5q-SMA
Objective: To determine the safety and tolerability of nusinersen treatment in ambulatory adults with spinal muscular atrophy (SMA) and investigate the treatment effect on muscle strength, physical function, and motor unit physiology.Methods: Individuals
Bakri Elsheikh +14 more
doaj +1 more source
Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]
ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R +5 more
core +1 more source
OBJECTIVE To explore the clinical and therapeutic effects of cervical plexus reinnervation for infiltrated or injured unilateral recurrent laryngeal nerve (URLN).
Songfeng WEI, Ming GAO, Yigong LI
doaj +1 more source
We present a heart transplant patient at his 17th year of uncomplicated follow-up. Within a frame of routine check out several tests were performed.
Joanna eWdowczyk +3 more
doaj +1 more source
Targeted Nipple Reinnervation in Gender-affirming Mastectomy Using Autologous Nerve Graft
Summary:. Our team recently described targeted nipple reinnervation (TNR) during female-to-male gender-affirming mastectomy with free nipple grafting using either direct nerve coaptation or nerve allograft.
Albert Y. Truong, MD +5 more
doaj +1 more source
The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice [PDF]
Gangliosides are glycosphingolipids highly enriched in neural plasma membranes, where they mediate a diverse range of functions and can act as targets for auto-antibodies present in human immune-mediated neuropathy sera.
Cunningham, Madeleine E. +4 more
core +1 more source
Experiments in laryngeal reinnervation [PDF]
AbstractLaryngeal reinnervation surgical procedures were performed in 26 dogs. Nineteen animals comprise the data reported in this thesis.Two different operative procedures were investigated, the ansa hypoglossi neuromuscular pedicle in 5 dogs, and the split phrenic nerve graft in 14 dogs.
openaire +2 more sources
Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. [PDF]
We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord.
Ghosh, Biswarup +8 more
core +2 more sources
Herpes Zoster Lesions on Reconstructed Breast Skin: Rare Objective Proof of Reinervation
Blazed up Herpes zoster lesions have been described in very few patients after free and pedicled flap transfer for reconstructive purpose. Although sensory recovery after flap reconstructions has been studied extensively most studies addressed subjective
Laurenz Weitgasser +3 more
doaj +1 more source

