Results 51 to 60 of about 17,567 (255)

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou   +14 more
wiley   +1 more source

Reinnervation bei einseitiger Stimmlippenlähmung

open access: yes, 2019
Hintergrund: Obgleich heute eine Vielzahl an konservativen sowie operativen Verfahren zur Behandlung der einseitigen Stimmlippenlähmung zur Verfügung steht, sehen wir in der Praxis immer wieder Patienten, die nicht ideal rehabilitiert sind.
Müller, A, Nasr, AI
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Reinnervation of the amphibian cardiac ganglion after complete or partial denervation

open access: yes, 1982
The interactions between regenerating and sprouted nerve terminals during reinnervation of neurones were tested in the parasympathetic cardiac ganglion in frogs. 1.
Ko, C P, Roper, S
core   +1 more source

Reinnervation post-Heart transplantation [PDF]

open access: yesEuropean Heart Journal, 2017
Heart transplantation results in complete denervation of the donor heart with loss of afferent and efferent nerve connections. The majority of patients remain completely denervated during the first 6-12 months following transplantation. Evidence of reinnervation is usually found during the second year after transplantation and involve the myocardial ...
Avishay, Grupper   +2 more
openaire   +2 more sources

Developmentally Guided Differentiation of Ventral Midbrain Dopaminergic Cells Validated in Proteopathy‐Based Parkinson's Disease Models

open access: yesAdvanced Science, EarlyView.
A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon   +12 more
wiley   +1 more source

Fiber type grouping during reinnervation after 1, 3, 9, 27 and 81 days of phrenicotomy.

open access: yes, 2014
Percentage of subjects showing fiber type grouping in hemidiaphragms during reinnervation.*: Significant difference in the mid-costal area at day 27 vs.
Stephan J. Schaller (678422)   +8 more
core   +1 more source

TRENDS IN MOTOR UNIT NUMBER ESTIMATION (MUNE) SCORES AS A PREDICTIVE FACTOR FOR FUNCTIONAL RECOVERY OF THE MEDIAN AND ULNAR NERVES

open access: yesПроблеми екології та медицини
Peripheral traumatic nerve injuries of the upper limbs, especially the median and ulnar, are a big problem for patients. These injuries can cause long-term disability and reduce quality of life.
A.M. Synhaivskyi, T.I. Nasonova
doaj   +1 more source

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang   +11 more
wiley   +1 more source

Chronology and mode of reinnervation of the surgically denervated canine heart: functional and chemical correlates

open access: yes, 1977
This study was undertaken to evaluate functionally the time and pattern of inotropic and chronotropic efferent cardiac reinnervation of the deneravated canine heart and to correlate functional data with regional myocardial catecholamine content and ...
D. V. Priola   +4 more
core   +1 more source

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