Results 61 to 70 of about 43,781 (290)

Maintenance of Genetic Diversity in Natural Spawning of Captively-Reared Endangered Sockeye Salmon, Oncorhynchus nerka

Diversity, 2014
Captive propagation of Pacific salmon is routine, but few captive breeding programs have been conducted to successfully re-establish extirpated wild populations.
Ruth E. Withler, David S. O'Brien, Nicolette M. Watson, K. Janine Supernault   +3 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Electronic Nose for Indoor Mold Detection and Identification

Advanced Sensor Research, EarlyView.
This study explores the potential of a SnO2 nanowire‐based chemiresistive electronic nose not only to detect but also to identify two common indoor mold species, Stachybotrys chartarum and Chaetomium globosum on two different growth substrates. In a laboratory setup, the electronic nose displays high classification performance using optimized linear ...
Hankun Yang, Martin Sommer, Stephanie Bauer, Uli Lemmer   +3 more
wiley   +1 more source

Habitat Suitability, Distribution Modelling and GAP Analysis of Przewalski’s Gazelle Conservation

Animals
Although the population of Przewalski’s gazelle (Procapra przewalskii) has increased, this species is still threatened by a variety of risk factors, such as habitat loss and fragmentation, grassland fencing, grazing conflict, the segmentation of ...
Dongni Liang, Chunwang Li
doaj   +1 more source

Marsh deer (Blastocerus Dichotomus) reintroduction in the Jataí Ecological Station (Luís Antônio, SP): spatial preferences Reintrodução de cervos-do-pantanal (Blastocerus dichotomus) na Estação Ecológica de Jataí (Luís Antônio-SP): uso do espaço

Brazilian Journal of Biology, 2005
Throughout the latter half of the twentieth century, wildlife habitat destruction and species extinctions have greatly increased. As the number of endangered species grows, the use of reintroduction as a conservation tool against species extinction ...
C. J. M. Figueira, J. S. R. Pires, A. Andriolo, M. J. R. P. Costa, J. M. B. Duarte   +4 more
doaj   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

The Portuguese Osprey Reintroduction Project: Achievements, Lessons and Perspectives

Пернатые хищники и их охрана, 2019
Ospreys (Pandion haliaetus) breeding distribution inPortugal comprised most of the coast until the beginning of the XX century. Thereafter, a continuous decline due to persistent persecution and habitat loss led the native population to extinction in ...
Luís Palma, Jorge Safara, Andreia Dias, João Ferreira, Marco Mirinha, Pedro Beja   +5 more
doaj   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source