Results 81 to 90 of about 124,475 (305)

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Habitat Suitability, Distribution Modelling and GAP Analysis of Przewalski’s Gazelle Conservation

Animals
Although the population of Przewalski’s gazelle (Procapra przewalskii) has increased, this species is still threatened by a variety of risk factors, such as habitat loss and fragmentation, grassland fencing, grazing conflict, the segmentation of ...
Dongni Liang, Chunwang Li
doaj   +1 more source

Marsh deer (Blastocerus Dichotomus) reintroduction in the Jataí Ecological Station (Luís Antônio, SP): spatial preferences Reintrodução de cervos-do-pantanal (Blastocerus dichotomus) na Estação Ecológica de Jataí (Luís Antônio-SP): uso do espaço

Brazilian Journal of Biology, 2005
Throughout the latter half of the twentieth century, wildlife habitat destruction and species extinctions have greatly increased. As the number of endangered species grows, the use of reintroduction as a conservation tool against species extinction ...
C. J. M. Figueira, J. S. R. Pires, A. Andriolo, M. J. R. P. Costa, J. M. B. Duarte   +4 more
doaj   +1 more source

Public health risk of Giardia and Cryptosporidium posed by reintroduction of beavers into Scotland [PDF]

, 2015
Following publication of ‘Scottish Beaver Trial Independent Public Health Monitoring 2009-2014 Report and Recommendations’ (Mackie, 2014), two pieces of complementary work were undertaken in parallel to assess the potential contribution of reintroduced
Auty, Harriet, Boden, Lisa
core  

Posterior Reversible Encephalopathy Syndrome and Azathioprine [PDF]

, 2019
Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome that presents with neurological manifestations, often associated with arterial hypertension.
Corte-Real, A, Vilas-Boas, S
core   +2 more sources

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Climate Action Impacts on Steelmaking Emissions of Persistent Organic Pollutants Highlight a Gap Between the Paris Agreement and the Stockholm Convention

Advanced Science, EarlyView.
Emissions of unintentionally produced persistent organic pollutants (UPOPs) and global warming are two major environmental challenges. But their governance has largely evolved in parallel, leaving the toxicity implications of climate‐driven industrial transitions poorly understood.
Yuxiang Sun, Qiuting Yang, Jianghui Yun, Yujue Yang, Junhao Tang, Qian Liu, Minghui Zheng, Guorui Liu   +7 more
wiley   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

The Portuguese Osprey Reintroduction Project: Achievements, Lessons and Perspectives

Пернатые хищники и их охрана, 2019
Ospreys (Pandion haliaetus) breeding distribution inPortugal comprised most of the coast until the beginning of the XX century. Thereafter, a continuous decline due to persistent persecution and habitat loss led the native population to extinction in ...
Luís Palma, Jorge Safara, Andreia Dias, João Ferreira, Marco Mirinha, Pedro Beja   +5 more
doaj   +1 more source