Results 91 to 100 of about 124,475 (305)

Shrinking the Malaria Map: A Prospectus on Malaria Elimination [PDF]

, 2009
\ud Thirty-nine countries across the world are making progress toward malaria elimination. Some are committed to nationwide elimination, while others are pursuing spatially progressive elimination within their borders.
Feachem, Richard G.A., Phillips, Allison A., Targett, Geoff rey A.   +2 more
core  

Phase locking a clock oscillator to a coherent atomic ensemble [PDF]

, 2015
The sensitivity of an atomic interferometer increases when the phase evolution of its quantum superposition state is measured over a longer interrogation interval.
Aspect, A., Bertoldi, A., Bouyer, P., Cantin, E., Kohlhaas, R., Landragin, A.   +5 more
core   +6 more sources

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Laboratory Rearing of \u3ci\u3eLycaeides Melissa Samuelis\u3c/i\u3e (Lepidoptera: Lycaenidae), An Endangered Butterfly in Michigan [PDF]

, 2017
The Karner blue butterfly (Lycaeides melissa samuelis) is listed as a federally endangered species in the United States. It occurs in oak savanna and pine barren habitats from eastern Minnesota to New Hampshire.
Bauer, Leah S, Haack, Robert A, Herms, Catherine Papp, McCullough, Deborah G, Miller, Deborah L   +4 more
core   +2 more sources

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Public perceptions of a white-tailed sea eagle (Haliaeetus albicilla L.) restoration program [PDF]

, 2015
The historic persecution and decline of European raptor populations precipitated the use of reintroduction as a species restoration tool in the late twentieth century.
Arts, Breitenmoser, Bright, Burke, Cairns, Carter, Dickie, Evans, Evans, Evans, Griffith, Hatzofe, Love, MacLennan, MacMillan, Madders, Marquiss, Marshall, Martinez-Abrain, Nilsen, Norman, O'Rourke, O'Toole, Pohja-Myrkä, Pope, Seddon, Thirgood, Whitfield, Wilson   +28 more
core   +2 more sources

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Identifying Important Areas for the Release of Five Endemic Species in a Mountainous Landscape: Inference from Spatial Modeling Techniques

Jurnal Manajemen Hutan Tropika
Efforts to release animals resulting from evacuation and rehabilitation into their natural habitats are important practices in wildlife conservation. Before releasing the animals, it is important to assess the habitat suitability of the areas to support
Dede Aulia Rahman, Misbah Satria Giri, Ahmad Munawir, Jacqueline L Sunderland-Groves   +3 more
doaj   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Evaluation of Potential Translocation Sites for an Imperiled Cyprinid, the Hornyhead Chub [PDF]

, 2018
Translocation of isolated species into suitable habitats may help to secure vulnerable, geographically limited species. Due to the decline of Wyoming Hornyhead Chub Nocomis biguttatus, conservation actions, such as the translocation of populations within
Hickerson, Brian T., Walters, Annika W.
core   +1 more source