Results 101 to 110 of about 113,150 (329)

LASMIK laser biorevitalization: mechanisms and therapeutic experience

Dermatology Reports, 2020
LASMIK laser biorevitalization is a well-known technology developed in Russia that is based on laser phoresis as a method to enhance percutaneous penetration of substances. The article describes the mechanisms that act here and factors that determine the
Sergey Vladimirovich Moskvin, Aleksandr Agubechirovich Khadartsev   +1 more
doaj   +1 more source

Age Progression and Regression with Spatial Attention Modules

, 2019
Age progression and regression refers to aesthetically render-ing a given face image to present effects of face aging and rejuvenation, respectively. Although numerous studies have been conducted in this topic, there are two major problems: 1) multiple ...
Li, Qi, Liu, Yunfan, Sun, Zhenan
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Mechanical Relaxation-to-Rejuvenation Transition in a Zr-based Bulk Metallic Glass

Scientific Reports, 2017
The relaxation of amorphous materials, i.e., aging, would largely endanger their performances in service. Here we report a mechanical relaxation-to-rejuvenation transition of a Zr35Ti30Be27.5Cu7.5 bulk metallic glass (BMG) in elastostatic compression at ...
M. Zhang, Y. M. Wang, F. X. Li, S. Q. Jiang, M. Z. Li, L. Liu   +5 more
doaj   +1 more source

Analysis of Software Aging in a Web Server [PDF]

A number of recent studies have reported the phenomenon of “software aging”, characterized by progressive performance degradation and/or an increased occurrence rate of hang/crash failures of a software system due to the exhaustion of operating system ...
Grottke, Michael, Liz, Lei, Trivedi, Kishor S., Vaidyanathan, Kalyanaraman   +3 more
core  

Strong rejuvenation in a chiral-glass superconductor

, 2002
The glassy paramagnetic Meissner phase of a Bi$_2$Sr$_2$CaCu$_2$O$_x$ superconductor ($x$ = 8.18) is investigated by squid magnetometry, using ``dc-memory'' experiments employed earlier to study spin glasses.
A. Gardchareon, A. Ito, A.J. Bray, A.K. Geim, B. Freitag, C.C. Tsuei, D. Petit, E.L. Papadopoulou, E.L. Papadopoulou, H. Kawamura, H. Kawamura, H. Kawamura, J. Magnusson, J. Villain, J.R. Kirtley, K. Binder, L. Lundgren, M. Matsumoto, M. Sigrist, M. Sigrist, M.S. Li, P. E. Jönsson, P. Granberg, P. Nordblad, P. Svedlindh, P.E. Jönsson, R. Lucht, R. Mathieu, R. Mathieu, R. Mathieu, T. Jonsson, T. Jonsson, T.M. Rice, V. Dupuis, W. Braunisch, W. Braunisch   +35 more
core   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

2013 age profile of the academic staff in universities, polytechnics and wānanga [PDF]

The ageing of New Zealand’s academic workforce requires careful management, however, universities now have a larger pool of ‘other’ academic staff from which rejuvenation of the senior academic workforce could occur.
Mieke Wensvoort
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source