Positive LGI1 Antibodies in CSF and Relapse Relate to Worse Outcome in Anti-LGI1 Encephalitis
Frontiers in Immunology, 2021 ObjectiveThis single-center study was conducted in a cohort of patients with anti-LGI1 encephalitis to investigate the factors related to their functional recovery.MethodsWe retrospectively collected the clinical information of patients admitted to ...
Li-li Cui +3 more
doaj +1 more source
Prediction of post-radiotherapy recurrence volumes in head and neck squamous cell carcinoma using 3D U-Net segmentation [PDF]
arXiv, 2023 Locoregional recurrences (LRR) are still a frequent site of treatment failure for head and neck squamous cell carcinoma (HNSCC) patients. Identification of high risk subvolumes based on pretreatment imaging is key to biologically targeted radiation therapy.
arxiv
Clonal selection and therapy resistance in acute leukemias: Mathematical modelling explains different proliferation patterns at diagnosis and relapse [PDF]
J. R. Soc Interface 11(94):20140079, 2014, 2013 Recent experimental evidence suggests that acute myeloid leukemias may originate from multiple clones of malignant cells. Nevertheless it is not known how the observed clones may differ with respect to cell properties such as proliferation and self-renewal. There are scarcely any data on how these cell properties change due to chemotherapy and relapse.
arxiv +1 more source
Social threat exposure in juvenile mice promotes cocaine-seeking by altering blood clotting and brain vasculature [PDF]
, 2016 Childhood maltreatment is associated with increased severity of substance use disorder and frequent relapse to drug use following abstinence. However, the molecular and neurobiological substrates that are engaged during early traumatic events and ...
Aricò, Eleonora +11 more
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
Frontiers in Psychology, 2011 Some evolutionary researchers have argued that current diagnostic criteria for major depressive disorder (MDD) may not accurately distinguish true instances of disorder from a normal, adaptive stress response.
Paul eAndrews +5 more
doaj +1 more source
A nonlinear relapse model with disaggregated contact rates: analysis of a forward-backward bifurcation [PDF]
arXiv, 2023 We developed a nonlinear differential equation model to explore the dynamics of relapse phenomena. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for individuals in each health class.
arxiv
, 2014 DCs are potent APCs and key regulators of innate and adaptive immunity. After allo-SCT, their reconstitution in the peripheral blood (PB) to levels similar to those in healthy individuals tends to be slow. We investigate the age- and sex-dependant immune
Bader, P +11 more
core +1 more source
Selecting the Optimal Unrelated Hematopoietic Stem Cell Transplant Donor for Relapse Prevention in Acute Myeloid Leukemia [PDF]
, 2020 Introduction/Background Hematopoietic cell transplantation (HCT) provides a cure for patients with acute myeloid leukemia. Natural killer cells (NK) play an important role in graft versus leukemia (GVL) effect after HCT, through killer immunoglobulin ...
Krieger, Elizabeth +2 more
core +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source