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Leprosy is unique in terms of the nature of the causative organism (Mycobacterium leprae), the chronicity of the disease, its prolonged treatment and the definitions of "cure" and "relapse." The principal mode of assessing the efficacy of therapeutic regimens in leprosy is the "relapse rate." There are wide variations in estimates of relapse rates ...
Kaimal, Sowmya, Thappa, Devinder Mohan
openaire +2 more sources
Relapse-free survival for patients experiencing remission of hypertension at 2 years after metabolic surgery (unadjusted Kaplan–Meier curve).
Erik Näslund (147859) +6 more
core +1 more source
Management of Relapsed and Relapsed Refractory Myeloma
Studies of bortezomib, thalidomide, and lenalidomide have shown promising clinical activity in relapsed/refractory multiple myeloma (MM). Bortezomib alone and in combination with other agents is associated with high response rates, consistently high rates of complete response, and a predictable and manageable profile of adverse events.
Kastritis, E. +3 more
openaire +5 more sources
Predicting the On-Study Relapse Rate for Multiple Sclerosis Patients in Clinical Trials [PDF]
Background: The annual relapse rate has been commonly used as a primary efficacy endpoint in phase III multiple sclerosis (MS) clinical trials. The aim of this study was to determine the relative contribution of different possible prognostic factors ...
Chang, C. +8 more
core +1 more source
Patients with severe substance use disorders are often characterized by neurocognitive impairments and elevated mental health symptom load, typically associated with craving intensity and substance use relapse.
Anders Dahlen Forsmo Lauvsnes +2 more
doaj +1 more source
Smoking increases the risk of relapse after successful tuberculosis treatment. [PDF]
BACKGROUND: Recent tobacco smoking has been identified as a risk factor for developing tuberculosis, and two studies which have investigated its association with relapse of tuberculosis after completion of treatment had conflicting results (and did not ...
d'Arc Lyra Batista, Joanna +3 more
core +1 more source
Objective To explore the novel applications of histological factors by stratifying the prognostic markers of the overall CRC patients in subgroups.Materials and methods A total of 17 histopathological and molecular factors were retrospectively collected ...
Yuan Yuan +4 more
doaj +1 more source
Brachytherapy for uterine cervix-limited acute myeloid leukemia relapse
Acute myeloid leukemia (AML) may extend to extra-medullary sites at diagnosis or at relapse, either isolated or associated with bone marrow disease. Granulocytic sarcoma of uterine cervix is rare, and there is no established treatment for this disease ...
Guillaume Beziat +7 more
core +1 more source
Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation [PDF]
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal +10 more
wiley +2 more sources
Relapse to smoking during unaided cessation: clinical, cognitive and motivational predictors [PDF]
Rationale: Neurobiological models of addiction suggest that abnormalities of brain reward circuitry distort salience attribution and inhibitory control processes, which in turn contribute to high relapse rates.
Jane Powell +16 more
core +1 more source

