Results 21 to 30 of about 4,730,453 (227)
Background Natalizumab is a monoclonal antibody approved for the treatment of patients with relapsing-remitting multiple sclerosis. According to the current clinical recommendations, its use during pregnancy should be carefully evaluated only in women ...
Elisabetta Godano +8 more
doaj +1 more source
Genomic regions associated with multiple sclerosis are active in B cells. [PDF]
More than 50 genomic regions have now been shown to influence the risk of multiple sclerosis (MS). However, the mechanisms of action, and the cell types in which these associated variants act at the molecular level remain largely unknown.
Giulio Disanto +32 more
core +1 more source
Quantification of cerebral tissue volumes in multiple sclerosis: global and regional analysis [PDF]
Brain atrophy has been reported in multiple sclerosis (MS). We addressed the question of GM and WM tissue loss in a large population of 597 patients with multiple sclerosis (MS) compared with 104 control subjects using a fully automated, operator ...
Prinster, Anna
core +1 more source
Background Disease-modifying therapies benefit individuals with relapsing forms of multiple sclerosis, but their utility remains unclear for those without relapses.
Sarah L Minden +5 more
doaj +1 more source
Cognitive impairment is a symptom of multiple sclerosis (MS). Different clinical forms of multiple sclerosis have different cognitive profiles, according to findings of previous studies which used extensive batteries of neuropsychological tests ...
Dóra-Neide Rodrigues +4 more
doaj +1 more source
Background Disease-modifying therapies are thought to reduce the conversion rate to secondary progressive multiple sclerosis. Objective To explore the rate, chronology, and contributing factors of conversion to the progressive phase in treated relapsing ...
Francisco Coret +9 more
doaj +1 more source
Cognition and cognitive rehabilitation in adult and juvenile patients with multiple sclerosis [PDF]
: Multiple sclerosis (MS) is accompanied by cognitive deficits in half of adult patients and in one third of children. These deficits have a serious impact on daily functioning of patients and may influence the ability to achieve educational goals and ...
Hubacher, Martina
core +1 more source
Although the causes of multiple sclerosis are largely unknown, genetic and environmental components play an important role. Geographic distribution, varying with latitude, reflects both genetic and environmental influences.
Gil Harari +4 more
doaj +1 more source
Evaluation of cognitive assessment and cognitive intervention for people with multiple sclerosis [PDF]
Objectives: Cognitive problems in multiple sclerosis are common but any possible benefits of treatment remain uncertain. The aim of the study was to evaluate the benefits of providing a psychology service, including cognitive assessment and intervention,
Weyman, N. +9 more
core +1 more source
Background Sleep disorders are common in patients with multiple sclerosis and have a bidirectional interplay with fatigue and depression. Objective To evaluate the effect of treatment with oral dimethyl fumarate on the quality of sleep in relapsing ...
Giancarlo Comi +14 more
doaj +1 more source

