Results 51 to 60 of about 3,062 (171)

Rare Gain‐of‐Function Variants in IDH1 and IDH2 Confer Increased Risk of Immune‐Mediated Rheumatic Diseases

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective Gain‐of‐function variants in IDH1 and IDH2 are enriched among individuals with coexisting myeloid neoplasms and autoimmune diseases. However, the association between IDH1/IDH2 variants and rheumatic diseases independent of hematologic neoplasms remains unclear. We investigated the association between rare gain‐of‐function and loss‐of‐function
Mahmut S. Kaymakci, Mehmet Hocaoğlu, Kenneth J. Warrington, Amr H. Sawalha   +3 more
wiley   +1 more source

C‐Reactive Protein Serum Values in Idiopathic and Autoimmune Subglottic Stenosis

The Laryngoscope, Volume 136, Issue 3, Page 1320-1326, March 2026.
This study characterized C‐reactive protein (CRP) levels in idiopathic and granulomatosis with polyangiitis‐related (GPA) subglottic stenosis (SGS) to assess CRP ability to distinguish SGS subtypes and predict recurrence. High CRP levels are more frequent in GPA‐SGS, potentially aiding clinical differentiation of etiologies.
Andrew J. Neevel, Fatemeh Ramazani, Julia Ford, Ora Gewurz‐Singer, Norman D. Hogikyan, Robert J. Morrison, Robbi A. Kupfer   +6 more
wiley   +1 more source

RARE RHEUMATIC DISEASES. RELAPSING POLYCHONDRITIS: A CLINICAL CASE

Научно-практическая ревматология, 2019
The diagnosis of a disease accompanied by febrile syndrome presents special problems in clinical practice. The traditional diagnostic algorithm in this case involves the exclusion of infections, cancer, and rheumatic diseases.
I. V. Semizarova, L. N. Eliseeva, A. F. Davydova, Z. A. Baste, Zh. A. Kisian   +4 more
doaj   +1 more source

Membranous nephropathy complicating relapsing polychondritis: A case report

, 2021
Background: Relapsing polychondritis is a rare systemic disease characterized by recurrent inflammation, and often destruction, of cartilaginous tissues. Renal manifestations are rare. Membranous nephropathy complicating relapsing polychondritis has been
Michael Clemenshaw, Vatsalya Kosuru, John Jason White, Christine Van Beek, Rachel Elam*, Christopher Rice, Laura Carbone, Leighton James   +7 more
core   +1 more source

Case Report of Acute Central Airway Obstruction Induced by Anti‐PD‐1 Sintilimab: Clinical Presentation and Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Immune checkpoint inhibitors (ICIs), such as sintilimab, have revolutionized non‐small cell lung cancer (NSCLC) treatment but can trigger immune‐related adverse events (irAEs). While pneumonitis is well documented, central airway obstruction (CAO) due to immune‐mediated necrosis is an extremely rare and life‐threatening phenotype that poses ...
Ting Ouyang, Zeqiang Wang, Weidong Zhang, Wei Liu   +3 more
wiley   +1 more source

Management of an extracranial internal carotid artery aneurysm secondary to relapsing polychondritis

Journal of Vascular Surgery Cases and Innovative Techniques, 2020
Extracranial internal carotid artery (EICA) aneurysms make up 1% of peripheral aneurysms and less than 1% of patients who have relapsing polychondritis develop aneurysms.
Kush J. Sharma, MD, Calla Heald, BFA, Justin M. Simmons, DO, Robert F. Cuff, MD   +3 more
doaj   +1 more source

Mapping VEXAS‐associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

British Journal of Haematology, Volume 208, Issue 1, Page 116-128, January 2026.
VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez, Leon Chang, Dorota Rowczenio, Alexandra Smith, Ebun Omoyinmi, James A. Poulter, Andrew McGregor, Sebastian Francis, Roochi Trikha, Adam Al‐Hakim, Kar Lok Kong, David G. Kent, Helen Lachmann, Austin Kulasekararaj, Catherine Cargo, Sinisa Savic   +15 more
wiley   +1 more source

Aortic involvement in relapsing polychondritis: case-based review

, 2021
Relapsing polychondritis is a systemic inflammatory disease that mainly affects ears, nose, eyes, joints, and large airway. Relapsing polychondritis may also affect cardiac valves and large vessels with the aorta being most frequently involved.
Erdogan, Mustafa, Hatemi, Gulen, HAMURYUDAN, Vedat, Esatoglu, Sinem Nihal   +3 more
core   +1 more source

Prevalence and comorbidity of relapsing polychondritis

, 2016
Jonas F Ludvigsson,1–4 Ronald van Vollenhoven5 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 2Department of Pediatrics, Örebro University Hospital, Örebro, Sweden; 3Division of Epidemiology and ...
van Vollenhoven, RF, Ludvigsson, Jonas F, van Vollenhoven, Ronald,, Ludvigsson JF, Ludvigsson, Jonas F.,, van Vollenhoven R   +5 more
core   +1 more source

Biodegradable Stents—A New Option for Benign Central Airway Stenosis

Respirology, Volume 30, Issue 12, Page 1176-1183, December 2025.
Airway stenting using conventional stents for benign central airway stenosis has considerable complication rates as well as technical difficulties while placing and removing. Polydioxanone biodegradable stents serve as a feasible alternative for individuals requiring temporary airway support.
Oğuz Karcıoğlu, Eda Burcu Boerner, Faustina Funke, Jane Winantea, Filiz Oezkan, Rudiger Karpf‐Wissel, Kaid Darwiche   +6 more
wiley   +1 more source