Results 71 to 80 of about 1,807,111 (288)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

BDHI: a French national database on historical floods

open access: yesE3S Web of Conferences, 2016
The paper describes the various features of the BDHI database (objects, functions, content). This document database provides document sheets on historical floods from various sources: technical reports from water authorities, scientific accounts ...
Lang Michel   +4 more
doaj   +1 more source

Workforce information database system to support production planning in construction projects

open access: yesJournal of Civil Engineering and Management, 2012
Information on the capacity of available workforce is important in production planning because a production unit's quantitative and qualitative capacities need to match its assigned loads. In the planning process, assigned loads and quantitative capacity
Sang-Chul Kim, Yong-Woo Kim
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

NanoBase: a tiny relation database manager for the JME CLDC/MIDP Platform

open access: yesRevista Tecnologia, 2009
Os recentes avanços obtidos na tecnologia de computação móvel possibilitam o desenvolvimento de novas e sofisticadas aplicações, as quais podem agora armazenar dados no próprio dispositivo móvel. A plataforma JME vem se consolidando como um padrão para
Leonardo Eloy   +3 more
doaj  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Development of a GIS-based, real-time Internet mapping tool for rabies surveillance

open access: yesInternational Journal of Health Geographics, 2006
Background Oral rabies vaccination programs have been implemented to control the spread of wildlife rabies in the United States. However, current surveillance systems are inadequate for the efficient management and evaluation of these large scale vaccine
Manangan Jamie   +5 more
doaj   +1 more source

ALIA LIS research environmental scan report [PDF]

open access: yes, 2014
Executive summary: An environmental scan of Australian Library and Information Studies (LIS) research was undertaken focusing on the period 2005–2013.
Christine Yates, Michael Middleton
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

CATEGORICAL RELATIONAL DATABASE MODELS [PDF]

open access: yesBulletin of informatics and cybernetics, 1984
A category of relational models and its quotient category are defined and their basic properties are discussed. Moreover a categorical join dependency and a category of adjoint models, which dualize the notion of relational models, are studied.
openaire   +2 more sources

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