Results 51 to 60 of about 8,736,695 (311)
The Digital Pandemic: Averting Negative Externalities of Disinformation Through Platforms
, 2022 In response to viral spreads of disinformation in the 21st century, most notably in 2020, this paper analyzes Section 230 of the Communications Decency Cct as currently written.
Cattich, Ryan, Elements
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The effects of recombination rate on the distribution and abundance of transposable elements [PDF]
, 2008 Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic ...
Charlesworth, Brian, Dolgin, Elie S.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Relationship between calcium decoding elements and plant abiotic-stress resistance
International Journal of Biological Sciences, 2008 Serving as an important second messenger, calcium ion has unique properties and universal ability to transmit diverse signals that trigger primary physiological actions in cells in response to hormones, pathogens, light, gravity, and stress factors ...
Wei-Yi Song, Zheng-Bin Zhang, Hong-Bo Shao, Xiu-Lin Guo, Hong-Xing Cao, Hong-Bin Zhao, Zheng-Yan Fu, Xiao-Jun Hu
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Position of the Artificial Intelligence Among the Elements of the Legal Relationship
Цифровое право, 2020 The development of artificial intelligence necessitates the legal regulation of social relations associated with the use of new technologies. Today, fragmented regulatory regulation is noted in Russian law, expressed, as the rule, in strategic documents ...
Anton A. Vasiliev, Yulia V. Pechatnova
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2001 Selenium as well as copper, zinc, and manganese play an important role in the detoxification of free radicals. There might be possible interactions with the mechanisms of action for cytostatic drugs as well as ionizing radiation.
Arbeitskreis Trace Elements and Electrolytes in Radiation Oncology (AKTE) (Germany)
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, 2022 This paper describes the connection between the foods we eat and our brain health. It asses the effects of certain nutrient groups on th ebrain and their role in the pathogenesis of Alzheimer's Disease (AD), specifically the brain abnormalities ...
Cohen, Caroline, Elements
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